Isometrics, IMHO, have their place. They are best used in the area where one gets stuck in difficult lifts, or at the most difficult spot in the range of motion of whatever exercise. But how effective they are varies a lot because you need to use a lot of effort in them to get a good result for either strength or hypertrophy or technical hiccup, and this can be hard to measure. They are great for rehab, like you say.
Although too taxing on the nervous system to do every week, I prefer supramaximal lifts with a shorter range of motion. This might mean adding 20-30% more than 1RM and either doing just the eccentric part (such as just lowering the bar part of a deadlift) or something like a squat where you lift a heavy bar an inch above the supports and just hold it there so it is easy to rerack. This gives considerable strength and psychological benefits, feels great when you drop back down to 85%, involves some ego lifting and can be somewhat dangerous without assistance or experience.
Isometrics are safe. A bar that doesn’t move, say on a Smith machine, is also very useful for doing easier pull-up variations, where you row your body to the bar by bending and straightening the knees while standing on the bench or the floor. An easy way to add volume for hypertrophy.
The opposite of isometrics, ballistic explosive movements with 15-40% are helpful. Jump squats using a hex bar or throwing light weights skyward on the Smith machine are my favourite ones.