One assumes that there were parts of the bill that Manchin was open to or even glowingly favorable towards. If not for those, they never would have had anything to haggle over to begin with.
It’s almost certain that you could take just the things that Manchin supports and pass those. Quite likely, you’d get a supermajority of the Senate to back it, a la the Infrastructure Bill. (Though, maybe not - see last paragraph.)
You can say that we’re not getting any of it because of Manchin. You could also say that we’re not getting any of it because of the progressives.
If you’re hearing most of the blame fall on the Manchin, it’s because you’re hanging around among liberals. But, the real way to look at it is that political leaning should - by nature - fall on a bell curve. Each party is made of two smaller skew curves that fit under that one, under the two tails, making up probably about 2/3rds of the population.
The third in the smaller bell on the left are angry. No one else is. 2/3rds are just fine or actively happy with Manchin. That’s a 2:1 ratio of support vs opposition to Joe Manchin.
Not only that, the people in the two smaller bells are both crazy. These are the people who will vote for Donald Trump and Edwin Edwards and complain that the other side is all corrupt and dishonest, and swear up and down with clear blue eyes that they’d never hire a disreputable crook to lead them.
Manchin may well be a corrupt bastard who works for Big Oil. I couldn’t say one way or the other. I’m not going to endorse the guy or claim him as part of my team. That would be crazy and I ain’t part of that crowd. Maybe if I lived in his district, I’d try to get a more solid answer on that one. But I strongly suspect that if you went with Manchin’s version of every bill for the next few years, the US would become a better place and get some basic, meat and potatoes, fundamental work done, and stories like that the Senate can’t function in a bipartisan manner, and that it’s impossible to pass anything without a filibuster would both take a hard hit. …Or, at least, that’s what Manchin and Sinema both seem to be driving for.
The crazies need that story to continue more than they want to pass the good parts of this package. You’re not getting anything good because if cooperation and compromise prove to be useful and good, then the crazies will lose 200 years of devoted work convincing you that you need to get more involved, enraged, and partisan. For their power, and ability to get into office and hold office - when 2/3rds of the government is opposed to them - that illusion is far more important than doing the good work.
The shared enemy of the crazies on both sides is the reasonable man, who just wants to do the good work. Gerrymandering and all other political machinations work mostly against the reasonable citizen, not against the other team.