I must say that Winsling and Miller offer an extremely compelling argument regarding the true nature of the Weapon X program. Unfortunately, when Stryker first encounters Wolverine, his first reaction is to express pride and satisfaction at his successful handiwork; if the “Wolverine as lab rat/first stage cyborg” theory were true, you would expect his reaction to be more along the lines of, “Jerk! Why the hell did you run off before we could install the Gadget-copter?”
Also, the first thing Stryker apparently did after Wolverine ran off was to make another adamantium-laced bodyguard. So obviously he thinks that this is somehow a good idea. It’s my theory that Stryker, having discovered the secret to creating liquid adamantium, is desperate to find a way to incorporate his discovery into any new project he gets involved in, whether it’s appropriate or not. If you hired him to remodel your house, chances are you’d hear, “…and you’ll never have to worry about the window screens tearing, since they have been bonded with liquid adamantium…”
This also ties in neatly with Fiver’s very reasonable objection regarding Wolverine’s ability to reject/eject foreign matter. In the comics, it has been revealed that Wolverine’s healing factor is the real reason why he was selected for the Weapon X program, since normal subjects tend to die of massive metal poisoning after recieving the adamantium treatment. In Wolverine’s case, his healing factor averts this effect, but at a cost: because of the adamantium, his healing factor only operates at a fraction of its normal efficiency. So this raises another question–why would you want to take a perfectly good mutant that is already practically indestructible, whose most impressive power is to heal instantly from any injury, and subject him to an invasive and superfluous procedure that will almost certainly kill him? Contrariwise, if the research was really to study the effect of adamantium bonding on a human, using a superhealing mutant as a test subject probably wouldn’t provide much useful data.
And even if they did manage to duplicate his healing factor somehow, enabling them to employ the adamantium-bonding process on a wide scale, what would you end up with? An army of guys with metal skeletons, which brings us back to the main issue at hand: a metal skeleton is practically useless! Oh, it’s a great idea if you have a job where you ski a lot, but otherwise it’s a fairly pointless upgrade. Yeah, you’ll feel real cocky and full of yourself with your new unbreakable skeleton, until you run up against Magneto. Or Pyro, for that matter. Or freaking Storm, or Iceman. Or basically any mutant that can kill you in a way that having an indestructible skeleton won’t protect you from, which let’s be honest is most of them. So the one thing that a metal skeleton will do for you is look really cool after you die.