There’s another ED-E activation when you talk to a particular someone at the Brotherhood of Steel (Not spoilered because, let’s be honest, you already know they’re in the game somewhere). After receiving that activation, the quest log no longer shows “Take ED-E to the scrapyard” and instead just says that key words appear to activate some sort of data log in ED-E, with no further information at this stage.
Also, I don’t want to spoil anything, but I will say you probably shouldn’t explore too much of the mystery of Vault 11 without some really, REALLY good armour and some decent firepower, along with plenty of Stimpaks.