Plnnr and obfusciatrist are exactly right. I once heard “Miller’s Crossing” criticized as follows:
“It was supposed to be about gangsters, but it was boring. There’d be parts where nothing happened for five or ten minutes except people TALKING!”
“I’m melting, I’m melting” (Wizard of OZ) Margaret Hamiliton (could be wrong)
“I’m unsinkable” (Unsinkable Molly Brown) Debbie Reynolds.
“My dope was duped. Or maybe my dupe was doped?” (Funny Girl) Barbara Streisand.
Coat check girl: “My goodness, what beautiful diamonds.”
Mae West:“Goodness had nothin’ to do with them, deary.”
“I’ve got half a mind to make that stud horse a gelding.” (Nine to Five) Dolly Parton.
Here are a few from The Lady Eve.
(Henry Fonda): I’ve spent my whole life studying snakes.
(Barbara Stanwyck): What a life!
later…
(Barbara): I can be as English as necess’ry.
And this comes from The Blair Witch Project.
(Heather) I am so, so sorry…
Finally, from Psycho,
(Janet Leigh) Oh crap, here comes that bird-lover, dressed like an old woman. Why’s he got that big knife?
[sub]I believe that may have been cut from the theater version.[/sub]
“I assume that’s your accomplice there in the wood chipper.” - Frances McDormand in Fargo
“Of course he has a knife. We all have knives. It’s 1183 and we’re barbarians.” - Katherine Hepburn in The Lion in Winter
“Stupid is as stupid does.” - Sally Field in Forrest Gump
“Don’t get mad; get everything.” - Ivana Trump in The First Wives Club
“I’m inviting you to come over and look at my Renoir…yes, it happens to be in the bedroom.” - Shirley MacLaine in Terms of Endearment
“Well, I figure when you take a state policeman, shoot up his car, take his gun and lock him in the trunk, it’s best just to get out of the state if you can.” - Susan Sarandon in Thelma & Louise
“I can handle it. And some of them are cute. And you are in no position to be jealous.” - Laura San Giacomo in sex, lies, and videotape
“What were his last words?”
“I’m coming.” - Goldie Hawn in Private Benjamin
“You can’t afford good liquor on an associate professor’s salary.” - Elizabeth Taylor in Who’s Afraid of Virginia Woolf
“I’ll have what she’s having.” - Billy Crystal’s mother in When Harry Met Sally
“You’re designated fuck.” - Linda Fiorentino in The Last Seduction
“I come from a very musical family. My mother is a piano teacher and my father was a conductor.”
“Where?”
“On the Baltimore and Ohio.” - Marilyn Monroe in Some Like it Hot
“Have you ever been mistaken for a man?”
“No. Have you?” - Carrie Henn in Aliens
Maybe the most quotable movie queen of all was Mae West. She wrote virtually everything she said on screen, having authored a string of hit Broadway shows before her movie career. My favorite of hers: “Is that a gun in your pocket or are you just happy to see me?”
Of course, the best line was cut from the final movie -
Sheriff (what was his name?): “Lady, you’re sucking on my arm!”
Sua
“Norman, you old poop!” On Golden Pond
What’s more memorable than old poop?? 
“Suck my dick”
Julianne Moore in Magnolia
Of course there’s a context, but anyway…
I thought it was Rob Reiners mother who had that line in “When Harry Met Sally”.
So I’m watching The Messenger: Story of Joan of Arc and it’s definitely a great source. (Milla Jovovich … ahhh…)
So here’s what I’m hearing:
Duc of Alençon: Put yourself in my shoes. How would you feel?
Jeanne: Knowing what I do? Enormous gratitude.
Jeanne: Listen, I know what I’m doing. So either lend a hand, or get back to bed.
Jeanne: I! AM! CALM!!
And probably more, but those stand out.
it is. See my prior posting.
Sure, wring that’s right, call attention to the fact that you said “CARL Reiner’s mom”, not Rob Reiner. [homer voice] D’uoh![/homer voice]
My goodness, Bill, do you really think the only movies with memorable female characters are “sentinmental women movies”?
Or that that is the only (or the obvious) alternative to prison movies and action flicks?
Still, in your honor, I will mention the ultimate chick flick (there are no men in it). Should you see it you can tell me if you think it’s mushy and sentimental:
“Jungle Red!” -The Women
Actually, I realized last night why Bill can’t think of any “famous lines.” Because he isn’t looking for “famous lines,” he’s looking for catch phrases. Clever little snippets that can be used by anyone, at any time, for nearly any purpose. Look at the examples he used: “I’ll be back,” “Yippee ki yay, motherfucker” . . . these have nothing to do with the context or plot of the film they’re in. They could appear anywhere.
It probably goes back to what obfuscatriast was talking about, the relative dearth of dialogue-driven movies in Hollywood. And writers who do use a lot of good dialogue – Tarantino, Mamet, etc. – write in genres where there aren’t a lot of good roles for women.
Since y’all mentioned Betty White and then took the quote away from her, I’ll revive the poor girl:
Also, someone mentioned Thelma & Louise:
I’ve had it up to my ass with sedate. --Thelma (Geena Davis)
You’ve always been crazy, this is just the first chance you’ve had to express yourself. --Louise (Susan Sarandon)
And, for recent films, Charlie’s Angels:
Chad: Was it the Chad?
Dylan: No, the Chad was great!
Chad with great emotion: The Chad was great.
And, finally, Christina Ricci’s characters have said a lot of great things since the Adams Family movies. For example:
My mother always told people she was her daughter’s best friend. Whenever she did, I thought, “Great, not only do I have a shitty mother, but my best friend’s a loser bitch.”
(from The Opposite of Sex)
Or perhaps the writers are writing what is true:
Men speak in 10 second sound bites.
Women speak of profound matters, utilizing their wisdom, great wit, insights, empathy…
Perhaps y’all are drawing from memory, or have a different script from mine. I have a copy of the Blazing Saddles book (!) subtitled, “from the screenplay,” and that section goes like this:
“Is it twue, schatzi, vot zey say about ze vay you people are gifted?”
Lili…flung herself down on Bart.
“I must find out…must find out…slurp, slurp…oh, oh, it’s twue! It’s twue, it’s twue, it’s twue…”
“Excuse me,” said Bart as diplomatically as possible. “I don’t want to criticize your technique, and this may have been what you had in mind all the time, but you’re sucking my arm.”
[end of quote]
Since movie books and other linked products are often prepared in haste so they can be released when the public’s fever is highest, I imagine this was drawn from an early version of the script. One can only guess why Mel Brooks left it on the cutting room floor. Does the scene play better without the additional line?
In the same vein as “I’ll be back”, there’s Carrie Anne Moss’s famous line in the Matrix: “Dodge this.”
Yeah, more power to us. 
Mia: Why do we feel it’s necessary to yak about b******t in order to become comfortable?
-Pulp Fiction
Lucilla: Is Rome worth one good man’s life? We believed it once. Make us believe it again. He was a soldier of Rome. Honor him.
-Gladiator
(I know there are a lot of famous lines- but this is a pretty good one. Sure, not as good as the my name is Maximus, father to a murdered son…speech, but still.)
The Exorcist was already mentioned, so I’ll have to skip it…
I don’t watch a lot of movies…I’ll get back to you later.
Oh wait. I like this one:
Col. Mustard: How many husband have you had?
Mrs. White: Mine or other women’s?
Miss Scarlet (and admittedly Mr. Boddy/Wadsworth): Communism was just a red herring.
Mrs. White: He was always a rather stupidly optimistic man, I’m afraid it came as a great shock to him when he died.
-Clue
ohhh…you beat me to that one.
I’d just like to add a few lines uttered by the girls in ‘Heathers’. Granted, not exactly ‘classic’, but they’re still stuck in my head.
“What’s your damage Heather?”
“No one at Westerburg is going to let you play their reindeer games”
“Dear Diary, my teen angst bullshit has a bodycount!”
“How very”
And my fave - Winona Ryder to Shannon Doherty: “Why are you such a megabitch?” “Because I can be”
I’ve never seen A Cry in the Dark, but it has that famous line by Meryl Streep about a dingo eating her baby (or something like that, I don’t know the exact quote).