Righto!
“I thought I’d seen some mean little gals in my time, but you’re the meanest.”
“If you had brain one in that huge mallet on top of your neck, you would be living the sweet life out in Southern California’s beautiful San Fernando Valley!”
I know it’s Bill Murray, i just can’t place the movie.
Stripes?
There are a couple others back up the thread a ways. Another one that sticks with me is “I don’t know such stuff. I only do eyes”. And everyone remembers “My mother? I’ll tell you about my mother”.
Or when Rutgers character says, “That…. hurt”.
“Which three books would you have taken?”
That’s the George Pal version of The Time Machine. Last line.
Correct!
You’re correct in that it’s Bill Murray, but no, it’s not Stripes.
“There’s four left in the box.”
Now that I read it again, it’s Venkman to Vigo in GBII.
“I can do anything I want. I’m eccentric.”
Rain Man
Yep, four matchsticks.
Yep.
“You flush it, I flaunt it.”
I thought they were toothpicks. Yeah, definitely toothpicks.
You’re right, my mistake! 
In Love at First Bite George Hamilton, as Dracula, says “I do not drink … wine. And I do not smoke… shit.”
(After Susan St. James has offered him a toke, saying “It’s really good shit.”)
“Why must I submit samples of my work to some stupid committee just to teach a thirteen-year-old girl?”
Wolfie, from Amadeus.