Okay, first off, the big picture. Trek universe vs. wars universe (the Force aside).
I saw a post on the first page of this absurdly-long thread (I only read the first and last pages) saying something about the entire Federation vs. the Empire. The Empire was listed as having 25,000 ships in this conflict (TIEs, I think, I forget), and the Federation (ENTIRE Federation) as having 300 ships. That’s absurd. In the Deep Space Nine episode “Favor The Bold,” the Federation fleet goes to retake DS9, only to encounter the Dominion/Cardassian fleet. The D/C fleet consists of about 1200 some-odd ships. Bashir states, “they outnumber us almost 2 to 1.” Half of 1200 is 600. And that was just one fleet (the Ninth Fleet, actually). I’m not certain, but I think the Klingons were there too (the Romulans weren’t pulled into the war until the last season). This seems to indicate that the Federation has AT LEAST 8 other fleets, which consist of probably around 300 ships (if you assume that the Klingon ships composed half of the fleet that set out to retake DS9). That amounts to about 2700 ships. And while there’s never been any mention of it, there may well be more fleets. And this doesn’t even count the Romulans, Klingons, Cardassians, the Breen, and the Dominion. Oh yes, and I seem to ahve forgotten the Borg, but that’s a whole other story. A combined fleet of Federation, Klingon, Romulan, Cardassian, Dominion, and Breen ships is at least possible, given the end of “What You Leave Behind” (at that time, the Federation, Klingons, and Romulans were already united against the Dominion, so treaties with them are possible, and the Federation signd a cease-fire with the Dominion as well, opening up possibilities for treaties, and the Dominion was aligned with the Breen and the Cardassians, so they might follow suit as well, AND with Garak helping to rebuild Cardassia, they might not be as antagonistic towards the Federation, with Garak’s POV in place). I don’t think the Borg are stupid enough to form a “temporary treaty” with those races, then attempt to turn against them when they’ve prevailed. The Borg would be fried. Anyway, there’s been discussion rwgarding whether or not transporters could get through Star Wars shields. This is, in the end, irrelevant, because Dominion ships are equipped with transporters that can get through shields anyway. Stormtroopers don’t stand a chance against Jem’Hadar warriors, especially with that dinky armor that doesn’t even protect them against a laser. They also have polaron beam weapons which punch right through Federation shields. The Breen have the energy dampening weapon. Klingons, Romulans and Breen all have cloaking devices, which would catch the Empire off guard. And the Federation… Well, okay, the Federation doesn’t have anything that’s particularly interesting, although several of their ships have been designed specifically to fight the Borg (Steamrunner, Akira, Defiant, Sovereign). Also, several of the new ships have ablative hull armor, which provides for a little protection. They’ve also got new blue (much better looking than the photon orange) quantum torpedoes. And then we come to the Cardassians. They’ve got spiral wave disruptors. Oh, well la de da. Cardassians were never very interesting anyway. Their only major accomplishment was the occupation of Bajor, and they eventually got kicked out anyway. Even when allied with the Dominion, they were just puppets of the Founders. So don’t figure the cardassian fleet having any major impact on the battle 
Oh yes, and the thing about the Star Destroyer’s energy source (black hole). Even if it’s not true, which has been stated, Romulan D’Deridex-class ships use an artificial quantum singularity as their power source as well, and these ships are also significantly larger than Galaxy-class ships (Galaxy-class ships are around 640 meters, so figure maybe…at least 700 meters, if not more).
And then, there’s possible intervention by the Prophets if Bajor (or even the entire Alpha Quadrant) were truly in danger, but that’s unlikely, and the only time they ever intervened was to make certain that Sisko didn’t die in “Sacrifice of Angels” (because he COULDN’T die, because that wasn’t when the game ends). They also had to save Bajor as well.
Anyway, the Borg vs. the Empire. Bye bye, Vader. Several people have mentioned that a Star Destroyer would destroy (I’m sorry, I’m sorry) a Borg cube easily. However, the Enterprise was barely able to even scratch the cube with their strongest phaser bursts. Barring Voyager (haven’t seen any of the Borg episodes, and the Voyager writers are on crack anyway), we’ve only seen a cube destroyed twice. The first time was in “The Best of Both Worlds.” It was destroyed by the Borg themselves, actually, not the Enterprise or the fleet that fought it at Wolf 359. When Data gave the cube a sleep command through Locutus, the cube set itself to self-destruct to prevent their technology from falling into Federation hands. So, no weapons there. The second time was in First Contact. The fleet defending Earth was fighting a losing battle until the Enterprise came in. Just listen to the voices heard over the comm chanel on the bridge. Admiral Hayes’ ship was destroyed (although Hayes survived, as Voyager later shows), the Defiant was a derelict (although salvagable), the Lexington apparently had many wounded officers (it’s one of the ships I remember hearing mentioned). The only reason the cube was destroyed is because Picard knew where to fire (an apparently-unobvious weak spot on the cube that even Data didn’t notice). Now, let’s consider the Star Destroyer. It’s got turbolasers, which may or may not be as powerful as phasers. Whoopty-doo. The Enterprise’s phasers didn’t do much to the cube anyway. We’ll never actually know if their deflector burst weapon would have worked against a Locutus-less cube (it failed because Picard knew of the plan; this knowledge was passed on to Locutus and provided to the Collective so they could adapt). However, it probably would have done at least very significant damage to the cube. But more than 78%? Cubes can operate even if 78% of it is inoperable, according to Shelby’s estimates. From what I can recall, this burst was designed to hit the cube in several places at once (although, in one big burst, meant to disable several systems at once). And they would only have one shot at it, since it would end up burning out their deflector.
Do Star Wars ships even HAVE navigational deflectors like the ones in Star Trek? If so, would they even bother to try making a weapon like that? In a one-on-one encounter, the ISD actually wouldn’t have the chance to make the weapon anyway (the Enterprise did actually have some time to work on the weapon). And this is just one cube. Even if it were to be destroyed, the rest of the ships would adapt to whatever destroyed the first ship and then go after the ISD to assimilate the technology capable of destroying a cube. Weapons aside, I seriously doubt that an ISD is anywhere near the size of a cube. From what’s been mentioned here, ISDs are 1600 meters long. Sovereign-class ships are nearly half that at almost 700 meters (680, actually). The cube in First Contact dwarfed the Enterprise. And that’s one cube. And this isn’t taking into account the ability of Borg ships to pop out of a transwarp conduit anywhere. One cube is under fire, send in 2 or 3 more through a transwarp conduit right behind the ISD and begin assimilation.
The entire Empire vs. the entire Collective (hell, half the Collective, or even 1/4) would end up with the Borg having tons of new ships and drones to play with.
Now, I’m not saying that either of these would be short battles, and the Trek sides (Fed/Rom/Kli/Card/Dom/Breen being one, Borg being another) would both certainly take vast casualties (the Borg would take less). But given technology levels, I’d have to say that the Trek universe gets the upper hand, in the end.
Of course, people might have already brought up all of this, I dunno. I’m just killing time.

