As someone in a serodiscordant relationship, I know about these things first-hand. Let me tell you a little something:
There exists an HIV/AIDS “underground railroad” of sorts. It began when the disease first appeared, because of lack of government funding and recognition - Reagan didn’t even utter the word “AIDS” in public until 1987, fully six years after the first cases of KS and PCP were reported to the CDC. Until AZT in 1987, there were no drugs. None. PWAs tried everything, including some experimental treatments, like suramin, that proved lethal. And even with the arrival of AZT (which, I should add, had been around since the late 1960s), it was a shoddy treatment at best, given in toxic doses, and nothing like the revolutionary HAART therapy that today we call “the cocktail.”
These drugs, and news of drug trials, travelled through the AIDS underground railroad. It was the relentless screaming of PWAs that forced the FDA’s hand in approving new HIV/AIDS treatments.
And even today, drugs are shipped - sometimes illegally - from one doctor to another, or to Africa, for example. If a doctor’s got a half a bottle of Videx and his patient who’s on it can’t afford his or her monthly script, guess who gets the Videx? It isn’t disposed of by a pharmacy. These drugs are motherhumping expensive. I don’t want to get overly political, but the pharmaceutical companies learned early on that HIV disease was a cash cow, especially since - like antidepressants and cholesterol drugs - these are “on it for life” drugs. Throwing out non-nucleotide reverse transcriptase inhibitors and protease inhibitors and fusion inhibitors is a nail in the coffin of every PWA out there who has to half his or her dose because they just can’t afford their monthly meds - if they have the meds at all.
Because of government inaction, and then resistance, HIV doctors also learned quickly that they had to fudge things such as disability claims, so that their patients wouldn’t fall through the cracks. This change happened mainly when doctors stopped treating wasting and death, and started treating a manageable chronic disease.
Anyway, to answer the question of the OP, I would not be offended. We say that HIV disease is not a gay disease, but first of all, a lot of poz people are gay men, and second, gay people have been so educated up the wazoo about HIV/AIDS and hopefully know enough about available resources that they would hopefully know what organization to contact to donate the unused drugs.