On one of thebroadcast networks (I’m thinking NBC.) Lasted only a few episodes. Was IIRC somewhat controversial. I remember a scene where a horse falls down a cliff, then explodes like a car in an action movie. At first I was thinking God, the Devil, and Bob, but it isn’t. Then I thought The Oblongs, but it isn’t.
Could be conflating with this scene?
After seeing your link I thought to google cartoon horse explodes (as I should have done in the first place) and answered my own question–it was Stressed Eric. Looks like I did pull some of the details from that Family Guy scene, though.