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Another vote for “I knew which video was in the OP’s link before even clicking on it.” 
It wasn’t actually shot in Studio 54, though the exterior shot of that club’s sign was undoubtedly meant to lead you to believe so. As per the song’s entry on Wikipedia:
Also, while I agree that Debbie often had that sort of tired/bored/stoned style in her videos (and she may well have been high during the shoot, for all the reasons already posted), there’s an interesting quote from her in that Wikipedia article:
I like this quote as well: Jess Harvell wrote that while "owning your own copy of ‘Heart of Glass’ may not seem as cool [anymore]… there’s the always luminous Deborah Harry, who would give boiling asparagus an erotic charge, all while looking too bored to live.
It’s pretty apropos comment IMHO :). As Blank Slate noted above she wasn’t necessarily a dynamic performer and she had that deadpan, I-don’t-give-a-shit stare perfected. Even as an actress her characters often came off as a bit detached and bored, but also wryly amused, which I think worked well for her.
Blondie was the first concert I ever went to.
Opening act was Nick Lowe (!).
Man, was that an awesome first concert.