Matthew Perry from Friends dies, RIP

In his book he talks about needing to take fifty-something OxyContin pills every single day. I can’t even imagine.

I know (or knew) lots of people who suffer that. They’re constitutionally incapable of being honest with themselves, or so I was taught.

A building I frequent has a bulletin board in the lobby covered with death notices. Some of the people died sober, some not. They’re all sad, but the former can be a comfort.

Totally understand, but it sounds like the Ketamine infusions were medically prescribed (from the linked article):

Perry, who rose to stardom playing Chandler Bing in the US sitcom Friends, was reportedly receiving ketamine infusion therapy for depression and anxiety before his death, Variety reported.

Which we could choose to view as different from a long-term and horrible prior pattern of addiction.

The CNN article I read said that his last prescribed ketamine infusion was two weeks prior to his death. Ketamine from that treatment would not still be in his body. The ketamine they found must have come from somewhere else.

Yes, that’s what I heard. The ketamine in his system was not from his medical care provider.

Yeah, well … shit:

According to the report, Perry reportedly was on ketamine infusion therapy and had a ketamine infusion one-and-a-half weeks prior to his death. However, the medical examiner concluded that the ketamine in his system could not have been from that infusion, as ketamine has a half-life of three to four hours or less.

SOURCE

It’s called Special K when bought on the street.

Incidentally, I’m not gloating, as that would be in very poor taste. But

I was likely correct.

Then again, as somebody who has also struggled with drug addiction my entire adult life (although never to Perry’s level), it wasn’t a hard thing to imagine.

Probably a pipe dream, but I really wish they would nail the dealer who was selling to him. Perry was responsible for his own actions (and had more resources than 99% of addicts to get help), but I cannot fathom the person that would keep selling drugs to a man who was clearly killing himself.

Yes, sadly, when an addict in recovery dies young, a relapse is a safe bet.

I can relate, believe me. I hoped he was sober, but too often that’s not how it plays out.

Tamoxifen, referenced and spelled incorrectly in thr article, is a long-term medication for estrogen-receptive cancer, not a weight-loss drug.

So it blocks estrogen? He was likely using that, in combination with testosterone injections (one side effect of taking testosterone is that your body converts some of it to estrogen), to try to get in shape. It’s the Hollywood way.

It’s a SERM (selective estrogen reuptake inhibitor). It blocks some estrogen receptors but not others. I suppose someone might take it to try to shift the estrogen-testosterone ratio, but I haven’t heard of that and it has some pretty lousy side effects, including weight gain.

ETA:

Possible side effects for men taking Tamoxifen include headaches, nausea, hot flashes, skin rash, fatigue, sexual dysfunction, and weight and mood changes.

–breastcancer.org

Isn’t this the business model of the tobacco industry?

I can’t think of any reason why a man would take tamoxifen, unless he was having some kind of condition where he needed the estrogen he does have blocked, and it certainly isn’t used for weight loss.

As for the dealer selling to a known addict, he obviously found out who would sell to him as long as the cash was green.

I’ve done a little reafibg and it looks like body builders sometimes use tamoxifen or aromatase inhibitors to enhance the effects of steroids. As someone who has to take tamoxifen, I can’t imagine doing so if there were an alternative, but there’s a lot about Perry’ chemical life that I’d never do.

^ ‘reading,’ but I couldn’t edit in time.

I just thought reafibg was some sort of medical database.

Nah, it’s a band name.

Reafibg is what you have with your Covfefe.