My least favorite X in/of my favorite Y is:

My least favorite season of my favorite TV show is season 5 of The Wire.

My least favorite song from my favorite musical is “Cool” from West Side Story.

My least favorite scene from my favorite Pixar Movie is the bit of The Incredibles where Elastigirl walks in on Mr. Incredible kissing Mystique (or whatever her name is). A rare dip into pure sitcom cliche…

My least favourite Beatles song is “Hold me tight” or maybe “Why don’t we do it in the road”. (If you count songs recorded by the Beatles on their studio albums but not written by them, I’d have to put “Till there was you” on the list).

My least favourite plot of the Harry Potter books is the main intrigue of Goblet of Fire (that’s the best plan Voldemort and his main minion could come up with? Please!)

My lesat favourite Sherlock Holmes adventure is “The Adventure of the Sussex Vampire”. (Could be solved by asking the main suspect “what the hell are you up to?”)

My least favorite movie by Tom Hanks is “Joe vs. the Volcano” (sorry if this isn’t exactly what you were looking for)

It is, as long as Tom Hanks is your favorite actor.

You really need to see Mazes and Monsters.

My least favorite album of my favorite rock & roll band is Pop, by U2.

My least favorite book by my favorite contemporary writer is Native Tongues, by Carl Hiaasen.

My least favorite recipe in my very favorite Vegan baking book (Colleen Patrick-Goudreau’s The Joy of Vegan Baking) is Chocolate Brownies. Don’t use applesauce in brownies!!!

My least favorite music video of my favorite singer is the video for “We R Who We R” by Kesha. I merely give it an A instead of an A+++ like all her other videos.

Yup, he is.

My least favourite episode of Babylon 5 is “Grey 17 is Missing”
My least favourite terry Pratchett book is “Monstrous Regiment”
My least favourite Cohen Bros movie is Intolerable Cruelty

My least favorite episode of Firefly is “Ariel”.