Need a recommendation for His & Hers 4-player video game

My friends (1 guy and 2 girls) are looking for a new 4 player video game. We have a PS 2, Xbox and Xbox 360. The ladies aren’t big fans of 1st person shooters and don’t seem too big on direct conflict with the guys (meaning us 4 against the computer is preferred).

Games that were a hit with both genders:
Hunter: The Reckoning
X-Men Legends II: Rise of Apocalypse
Worms Forts: Under Siege (even though it’s only direct competition)
Circus Maximus: Chariot Wars
Smack Down vs. Raw 2007 (if only for the Royal Rumble)
Fusion Frenzy

Both ladies really liked Star Wars: The Complete Saga, but alas it’s not 4 player.

I’ve have an open mind, so do you guys have any recommendations?

Mariokart.

Marvel: Ultimate Alliance is by Raven, the same studio that did the X-Men: Legends series. Your starting team consists of Captain America, Thor, Wolverine, and Spidey. Gameplay is essentially the same, but they tweaked the way you develop the characters’ stats.

Rock Band. Thank me later.

Super Monkey Ball.

This thread is now closed.

Uh, Mario Kart and Super Monkey Ball aren’t available for the systems the OP listed. I’ll second Ultimate Alliance. That game is fun.

Rock Band, Rock Band, Rock Band!

If you are up for competing against one another, Scene It for the 360 is a lot of fun and includes special controllers for each player that makes you feel like being on a game show.