My two cents (LONG)
I use the D100 professionally all the time, and the answer to the OP is a qualified yes. All AF Nikkor (and most Nikon style AF third party) lenses work quite well. There are some issues with older manual lenses - they also work, but you lose some if not all TTL metering. That’s not as bad as it sounds - I use an old Nikkor 28-120 constant 2.8 MF all the time, and I just make sure that I check the histogram for proper exposure and shoot in RAW mode.
And yes, beware the focal length multiplier (yes, 1.5 for Nikons, 1.6 for Canon) - it’s wonderful if you tend to go with longer lengths anyway, but my gorgeous and extremely pricey Nikkor AF 18 MM 1.4 is now the functional equivalent of a mid-range 27 MM, albeit with significantly nicer optics.
As for the S2 - yes, quite a decent camera as well, but I MUCH prefer the D100. I’ve logged a fair amount of time with both, as well as with the Canon 10D (which is also quite nice), and the D100 seems to hold up better, and just feels a bit more there.
Not to knock the S2 - but the Firewire connection, while nice, isn’t the be all and end all of camera-PC connections. If you’re shooting RAW (which you really should be if you want to maintain full control once the pic is downloaded) you’ll be using multiple cards anyway. A dedicated card reader, to my mind, is actually quicker than plugging in the camera, unloading pics, unmounting the device, swapping cards, etc. but YMMV.
The biggest advantage of the S2, IMO, is the on-camera PC connector. Doesn’t bother me overly much, as I use IR triggers instead of cables for studio work, but it would be nice to have one. That said, the SB-80DX DOES have a PC connector on it.
Speaking of flashes, the -28DX is nice, but if you can possibly afford it, go for the 80DX - the additional features and much faster recharge time make it well worth it. Plus, it’s got a really cool stroboscopic flash function for some pretty cool motion capture effects.
And lastly, if you go D100, you MUST get the MB-100 battery grip. It holds two of the LI batteries and I’ve NEVER even used up the juice in one. I’m currently in the midst of a battery life experiment where I’ve got both batteries in the grip until I run out of power. (I’ve got a couple spares stashed in case that happens during a shoot). I haven’t even gone beyond the battery full indicator on ONE battery yet (checked by pulling the other battery out of the compartment) and it’s been two months of moderate to heavy professional shooting (300-800 shots/week), although I must admit, I never use the flip up on camera flash. So battery life is not an issue. Plus, it comes with a AA holder for emergency use (and the SB-80DX takes AAs, so you’ll probably have them in your bag)
But the better feature of the MB-100 is the vertical grip, shutter release and command dials. They give the camera some real heft (like an F100 or F5) and once you start using a vert grip you’ll never go back. Of the bad side of the mb-100, I don’t know a single pro who actually uses the stupid voice recording feature. I suppose it might be useful in the field where I didn’t have a pen, but heck, I’m a concert photographer. The music would drown out whatever I tried to say anyway…
Sorry to ramble, but hey, I’m a photographer…we tend to have a bit of the techno-weenie in us.
KTM
PS Chefguy - what lenses are you selling?