Chuck
Benson
Mary Hartman, Mary Hartman
Punky Brewster
Alf
The Partridge Family
The Brady Bunch
Amos and Andy
The Beverly Hillbillies
Malcolm in the Middle
The Life of Riley
Hank
Arnie
George and Leo
Our Miss Brooks
The Many Loves of Dobie Gillis
Rango
Gilligan’s Island
Dusty’s Trail
Bronco
Sugarfoot
Cheyenne
Maverick
The Life and Legend of Wyatt Earp
Bat Masterson
The Virginian (AFAIK, he didn’t have another name)
The Guns of Will Sonnett
The Travels of Jaime McPheeters
Alias Smith and Jones
Hec Ramsey
Amy Prentiss
Owen Marshall
Chico and the Man
Magruder and Loud
Holmes and Yoyo
Bat Masterson
BJ and the Bear
Sheriff Lobo
Eischied
Hope and Faith
The OP mentioned Mork & Mindy, but not Laverne & Shirley?
Since The Mary Tyler Moore Show was brought up in the previous thread, we need to recognize:
Rhoda
Phyllis
Lou Grant
Others I don’t think I saw upthread:
Enos
Matt Houston
Lobo
Archie Bunker’s Place
and arguably Wild Wild West
It seems from reading the thread that spin-offs are frequently named for the characters they spin off. That makes a lot of sense, since someone browsing the TV Guide might not know that Just the 10 of Us features the Coach from Growing Pains they always laughed at, but even if you hadn’t heard anything about Rhoda or Frasier getting their own show, when you see the listing it’s obvious what’s happened.
Looking back, I find it interesting that in the earliest days almost every show was named either for the character or the actor.
From 1949-50, the first season with long-running sitcoms I find:
The Aldrich Family
The Life of Riley
Lum and Abner
Wesley
There was also Heavens to Betsy, a title they loved so much that they gave it to another unrelated show in 1952, Heaven for Betsy, starrring Jack Lemmon. And that was his second second lead role.