Ha! I get to be the one who nominates Betty Rubble.
Also a “me too” for Calvin’s Mother.
You start a new thread on this, and he’s got my top vote.
In terms of comics I mostly read manga these days; girls’ (shoujo) and women’s (josei) manga in particular is full of impossibly good-looking people of both sexes. For instance, the supernatural form of the title character of The Demon Prince of Momochi House. Along with another 90% or so of the cast.
The definitive treatise on the subject.
From the OP:
Appears I’m already in the right thread, thanks.
My darling Miss Terious
It’s gotta be the redhead Caitlin Fairchild from Gen13…
Tiffany from Luann. Still rooting for Gunther to exchange bodily fluids with her.
I said most attractive, not most promiscuous!
Mam-selle Hepzibah, in Pogo (an anthropomorphized skunk).
Miss Buxley (Beetle Bailey)
What, no love for Futurama? Leela and Amy are hot!
And thank Og for Rule 34!
You say that as though it were a bad thing… :dubious: 
OMG, YES, YES, YES!!! :o
We definitely park our cars in the same garage! 
I must confess: I also dig Meg “Jail Bait” Griffin on Family Guy! :o
Shut up, Meg.
Well, consider it from Annie’s point of view.
This far into the thread, and no one’s mentioned Melody on Josie and the Pussycats? :dubious:
I considered it. Oddly, Frankenhoff’s 100 SEXIEST WOMEN IN COMICS includes Betty and Veronica, but not Melody…whose main schtick was being so incredibly sexy that boys’ eyeballs did the Warner Bros cartoon thing when she sashayed past in her miniskirts.
I dig Josie, too. Redheads, mmmmmmmmmmmm! :o