Top notch female martial artist versus 6' 4'', 250 pound man -- Who wins?

But the differences between a trained 140 lb. woman, and a trained 140 lb. man, are enormous. Therefore it is very problematic to use what a trained smaller man can do against a larger untrained man as an indication of what a trained smaller woman can do against an untrained larger man. I am not saying she is doomed no matter what - there are no guarantees in fighting. But she is at a very serious disadvantage in the last two scenarios.

I’ve been on the long end of this kind of a match-up in sparring. I was nowhere nearly 110 lbs. larger - more like 30-40. And the skill disparity was probably roughly what it would be in scenario #3. I was considerably stronger in the upper body than even national champion-level women. And that makes a big difference.

Regards,
Shodan