It’s a metaphysical certainty that he isn’t wearing pants. Beyond that, I cannot bear to speculate.
ETA: I’m going to try to do a better job of multi-quoting in a single post. Discourse didn’t snap at me this time, but I know I fall short on that one.
I have another reason to detest Rudy: He was the lead attorney representing Purdue Pharmacy in 2006. I was unaware that Rudy defended the scummiest rich family around, the Sacklers. I didn’t know this history very well and just watched the show series called Painkiller and I recommend it if you haven’t seen it. I have a few new things on my reading list to get through.
A while back, an alcoholic friend of mine was going in for surgery. He thought it was pretty cool that the doctor asked him to sneak in some booze as that facility didn’t have the resources to deal with him going into withdrawal while he was there.
When I mentioned that here, I was informed that some (many? all?) hospitals keep vodka in the pharmacy specifically for dealing with people that do end up in that situation.
Glad I noticed the “For ORAL use only” tag at last. I feared it’d be given intravenously…
ETA: seriously though, it makes perfect sense. The doctors wouldn’t want to get someone into delirium tremens when in need of care/surgery for a different issue.
Shouldn’t be a problem here with universal healthcare (including emergency booze as it seems), but if they rather want to send a hooker with champagne, who am I to complain?
Ordinarily it’s just the first step prior to pumping your stomach out and further treatment.
Treatment options for methanol toxicity include supportive care, fomepizole (Antizole, 4-Methylpyrazole or 4MP), ethanol, dialysis, and theoretically, folate. Fomepizole is the antidote for toxic alcohols, and its mechanism of action is the inhibition of alcohol dehydrogenase. Ethanol may also be utilized therapeutically to inhibit alcohol dehydrogenase when fomepizole is unavailable.
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Fomepizole or ethanol serves as alcohol dehydrogenase inhibitors to stop the conversion of methanol to its toxic metabolite, formate. When alcohol dehydrogenase is inhibited, clearance of methanol is prolonged from approximately 8.5 mg/dL/hr to an effective half-life of 45 to 90 hours. Fomepizole is given intravenously, with a loading dose of 15 mg/kg, and then maintenance dosing of 10 mg/kg every 12 hours for 4 doses or until the methanol concentration is less than 32 mg/dL with normal acid-base status.
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Dosing of ethanol is more complicated, difficult to monitor, and has the added side effect of inebriation. Ethanol may be given intravenously or orally. However, it should only be given if fomepizole is unavailable as it would be inappropriate to cause the patient to be inebriated for such an extended period.