Is there anything in the Bible stating that God has a “hand of protection” specifically over America? Or a special protection over one country, the largest in the world, which can be taken to mean America?
Well, you have to realize that America as we know it didn’t exist when the Bible was written, and instead was inhabited by savage heathens (a joke, people!).
Anyway, since nobody who wrote the Bible had the gift of prophesy, no. There is nowhere in there that says that God has a “hand of protection” over America. The only way it might would be somewhere in Revelations.
The OP reminds me of the Texas governor who opposed bilingual education in public schools by declaring, “If English was good enough for Jesus Christ, it ought to be good enough for the children of Texas.”
I’ll stay as factual as possible.
As Speaker for the Dead points out, the New World was unknown to the Old World when the Bible was written down, and so the Bible does not explicitly refer to the United States. A popular theme in Christian apocalyptic literature, particularly in the 1970s and 1980s when the United States was facing the Soviet Union in the Cold War, was identifying metaphors in Isaiah or Revelation (for example, “Gog” and “Magog” in Rev. 20.8) with modern nation-states–probably the most successful entry in that genre was The Late Great Planet Earth by Hal Lindsey–but that exercise has been underway since ancient times, and point to America no more clearly than they pointed (or point) to the Roman Empire or the Holy Roman Empire or the European Community. More recent books, such as The Mighty Hand of God by Dale Evrist (which I have not read), have developed the concept of God’s “hand of protection” over Christian people, but I don’t know if those books draw a scriptural connection between God’s protection and the United States in particular.
The Scripture that is usually cited for God’s protection over Christian people is 2 Chronicles 7.14: “if my people who are called by my name humble themselves, pray, seek my face, and turn from their wicked ways, then I will hear from heaven, and will forgive their sin and heal their land.” But that verse does not directly refer to America or any other nation, only to “my people who are called by my name”–which, in America’s case, would refer only to some particular religious group rather than to the entire nation.
The only Scripture that I can find that is a close match with your question is 2 Samuel 22. Verse 44 says, “You delivered me from strife with the peoples; you kept me as the head of the nations; people whom I had not known served me.” Earlier in the same chapter, verse 31 says, “This God–his way is perfect; the promise of the LORD proves true; he is a shield for all who take refuge in him.” The chapter therefore combines the concept of “the head of the nations” and the Lord as a protector. Read into it what you will.
If the Bible did make reference to the largest country in the world in our times, this would turn out to be Russia (by land area) or China (by population). I would think that the sort of people who live their lives according to Biblical prophecy would be rather upset if either of the above were specially protected by God!
However, I’m sure that there are any number of Nostradamus predictions that could be massaged to support the OP, since he was smart enough to cover all the bases. 
Obviously I didn’t mean mentioning America by name, but referring to a country which will (future tense at the time) be the largest and most powerful.
Largest and most powerful today (USA) is not Largest and most powerful from 100 years ago, or 200, or 300, or 400… you get the idea. The United States is not the largest at all, and never has been. It is only recently the most powerful, and that is not guaranteed to last all that long.
I obviously meant the “(USA)” to refer back to the adjective “powerful”, and not the adjective “Largest”.
I was going to make a crack about the Bible not being written in English, but since peepthis has beaten me with a variant, I’ll turn this around and note that the line he quotes is a joke that has been around forever and has been attributed to just about anyone and everyone.
Many people give the “credit” to Texas governor Miriam “Ma” Ferguson who said this in a debate about 1924 or some other time or some other occasion. A few sites say that it was her husband, James Ferguson, whom she succeeded as governor, who said it first in 1917, when vetoing a bill.
I don’t find any contemporary citations for this, and the exact quotes given vary considerably. And none of the sources make it clear whether either one of them might have just been making a folksy joke in the first place.
I will also make the factual observation that people have often interpreted the words of the Bible to refer to their own times and own peoples for all the thousands of years that it has been disseminated.
This seems to be a question George W. Bush would be happy to answer.
Another famous example is Nostradamus’ writings.
Note that when it comes to the New Testament, Jesus has less concern for physical, political kingdoms of this world. As a non-US citizen myself, there’s nothing in the Bible that really suggests that God is looking out for any country, save perhaps Israel (and that’s because of their old pact in the Old Testament).
It seems that Jesus is more concerned with individuals, than with countries in general.
Just my two cent worth.
NOTHING!
Any questions?
I disagree.
RR
I went to the Bible Gateway, and searched for “hand of protection” in the New International Version, the New Standard Version, and the King James.
Nothin’.
Doesn’t the Book of Revelations say that eventually every government and other source of authority will cease to exist? This is supposed to be one of the signs of the End Times.