Was reminded in another thread. While getting a third opinion on surgery for s floppy heart valve, we were impressed/amazed/laughed when the cardiologist said “I bet you have flat feet,” because it seemed so out of the blue.
He then explained how the tissues involved react similarly throughout the body for whatever the heck was happenening in the heart. But I can’t remember anything more.
What was he referring to?
Don’t know the answer, but if you’re headed for heart surgery, wish you the best, Leo! Hope it all goes well. 
Marfan syndrome? Due to congenital abnormalities in connective tissues, ligaments are floppy and overlong. Flat feet and heart valve disorders are in the symptom list.
But I thought it’s pretty well characterized; if you had it, someone would have diagnosed it already and you’d recognize it.
You’re not tall, gangly, long-limbed, and loose-jointed, are you?
OP here–NP, everyone else reading: thank you for your concern, but this is way in the past and was actually an issue with my wife, who does not have Marfan’s, and is happily running around with a gurgle here and there.
She’s 5’-7" or so. Interestingly, and as a coincidence, just yesterday she taught me the phrase “monkey arms,” and her possessing them, both of which were unknown to me. I learned this basic fact about her (who says marriages are intimate) when I complained about how sad it was I couldn’t pet my dog’s head while we walked, and then she was all over him without reaching.
Fifteen years ago some prick of a cardiologist at Lenox Hill, world famous for minimal invasive surgery, suggested then and there at our first meeting with any doctor that she check in for the knife. Can’t have too many data points for this guy. Scared the crap out of us.
Crosstown 2nd opinion to Cornell Presbyterian, Doc says Sheesh, get out of my office, go skiing, you’re fine.
Third Dr., Mr. Flatfoot, concurred with second one.
My late husband definitely didn’t have Marfans, but there was SOMEthing up with his connective tissue genes. His arms were long for his height (I called them pterodactyl arms, for the way he looked when he stretch them out bird-wing style … Same idea as monkey arms, though!) and his skin was very stretchy compared to mine and most people.
Makes sense that similar tissue would have similar stretchiness throughout an individual’s body, though I’m sure lots of different proteins are involved.
Not sure if this is precisely what he was referring to but some people have variants of collagen that are stretchier than others. It can sometimes be labelled “benign hypermobility syndrome” and sometimes Ehlers Danlos Syndrome (EDS) Type 3, partly based on who is doing the naming and partly based on degree of hypermobility (stretchiness). Mitral valve prolapse (MVP) is not uncommon among them and the converse is even more true - many of those with MVP have joint hypermobility. Classical EDS also has the stretchy skin, sometimes poor wound healing, and about half of them have MVP. Type 4, vascular type, is much less common. Yes Marfans and also Osteogenesis Imperfecta can cause both as well.
But the most common would be Type 3 EDS/Benign Joint Hypermobility causing both.
Reminds of the supposed connection between creased earlobes and Coronary Artery Disease, not sure if that one is true but it was supposed to be related to lost elasticity in the blood vessels.