Good vacation spot: Washington, DC. Nice location, you can drive to the whole Eastern Seaboard easily, great museums and sites of interest (Library of Congress my favorite, esp. the reading rooms. Beautiful!), plenty of authentic restaurants (plenty of recent immigrants as well, English is understood to varying degrees everywhere, though), and a nice climate (Humidity? Go to the Gulf. That’s humidity!).
Best place for a steakhouse tour: Kansas City, MO and KS. If you can get past the smell of stockyards a few miles to the west, you’ll enjoy the best red meat you’ve ever had. Steak in that town is good and realtively cheap. Nothing beats good old cornfed American!
Best place on the Mississippi: St. Louis, MO. (East St. Louis, IL, is essentially a slum. Don’t drive through after dark, and don’t tarry there at all.) Great place for blues, steak, and history. If you’ve ever wanted to study the Big Muddy, do yourself a favor and view it from the top of the Gateway Arch.
Best place in the Rockies to base a vacation from: Missoula, MT. Only a stone’s throw away from Flathead Lake (Extremely scenic, extremely boatable, extremely cold lake in the Rockies. It’s glacier-fed, making it crystal-clear and frigidly cold.) and some of the most beautiful roadway this country has to offer. I’d suggest Going-To-The-Sun Road for breathtaking driving with pull-offs for picture taking. Don’t attempt it in the winter, though, because it will be icy even if the city is dry. Heck, that’s true of every mountain pass in Montana! Missoula is also a nice shopping town, with a Costco (Dirt-cheap bulk wholesale. They sell everything, and they sell everything in bulk. You can find toilet paper cheaper than some places sell candy bars, but only in 50-roll packs. Don’t buy perishables unless you’ll actually eat 50 pounds of rib roast.) in town. And, as a refreshing aside, you can buy things at a Missoula grocery store (Buttrey’s is good), drive your car around to the loading lane in front, and bagboys will load your stuff for you.
Great shopping town: St. Paul, MN. The Mall of America, the biggest damn retail center in America, is in St. Paul. Like Costco, you can find anything in The MoA. Unlike Costco, it’s retail. Plan to spend plenty, but on a bewildering variety of shops. There’s even an amusement park, complete with flume ride and roller-coaster, inside the building itself. It’s at least a few days to see it all, and plan on getting very sore feet. Hey, it’s a workout.
This doesn’t get even close to all the cities I could recommend (Cape Girardeau, MO, for Broussard’s, a great cajun restaurant; Ely, MN, for a great rural northern Minnesota vacation spot in the famous North Woods; etc.) but this post is running on and on. I’ve lived in various places, and I’ve traveled to many, many others, including Europe. I’m just glad I could and did. 