What's the funniest single panel cartoon you've ever seen?

The Kliban Nixon Monument panel was the first grown-up comic that I experienced. It was a long ways from Peanuts and Dennis the Menace.

Lots of good older stuff here, but Tundra is one of my current favorites. I like this one from 2011: The Last Alien Abduction.

These are the funniest? Ever?

http://www.condenaststore.com/-sp/O-K-you-be-the-doctor-and-I-ll-be-the-Secretary-of-Health-and-Human-Se-New-Yorker-Cartoon-Prints_i8540589_.htm

Being a live music fan, I’ve always had a soft spot for “Raymond’s last day”

Not exactly rocket science
https://au.pinterest.com/pin/78250112246699449/

Well, they finally came …
https://au.pinterest.com/pin/125115695874114277/

This cracks me up every time I think about it.

I cannot find it, but I have a strong recollection of a Gahan Wilson panel in Playboy sometime in 1978 where a grubby cook is in a dingy diner bathroom, scrubbing something in the sink. Beside him is a pail of severed human hands. Next to the mirror is a sign saying, “Employees must wash hands before cooking.”

Second fav is an old Thurber panel: why did you answer?

Dirty, scaly chicken toes. Harry sticks them up his nose.

Why oh why can I remember that Kliban cartoon for decades when I always have to look up the dose of rifaximin every time I have to prescribe it? :smack:

Premature

I think Mike Baldwin is a brilliant cartoonist. For me, his best work is up there with Larson. My favourite is this, which is not only very funny but also highly ingenious:

There’s a lot more of his work to enjoy at Cartoon Stock. Check it out!

I nominate this one by Charles Addams for best uncaptioned single panel cartoon.

James Joyce’s Refrigerator

OR

Kliban’s Contribution to the Sciences

“Wendell… I’m not content.”

Suck my Florida would have been a lot funnier.

I have no idea how to find it, but one of my favorites was also a Farside. A guy standing on the bottom of the ocean in one of those diving suits that doesn’t have its own air supply, but is supplied by hose from a compressor up on the ship. He’s looking up as the ship is sinking above him.

A great one, to be sure, but as it contains three panels I don’t think it meets the thread criteria…

Absolutely what I came to post, Mr. Dibble!

And let’s not forget Jim Unger’s Herman.

Once again Larson:

As I had this coffee mug, the one penguin among thousands is what comes to mind first to me: http://middleagedmormonman.com/home/wp-content/uploads/2015/04/i-gotta-be-me.jpg

I can’t find this on line, but this cartoon reprinted in “The Prehistory if the Far Side” always cracked me up: You’re looking out from the inside of a castle, and Doctor Frankenstein is answering the door with the monster next to him (not visible from the doorway), the callers are Dorothy, the Scarecrow, the Tin Man and the Lion, and the caption reads, “Sorry, I just used my last heart and brain - maybe try the wizard down the road.”

This New Yorker item has always been a personal favorite.