It certainly would be easier now where (assuming it exists) the theater can download the projection file rather than shipping a bunch of cans from a depository in who-knows-where. In a pinch you can even use a Blu-Ray disk (with permissions in place, of course).
Fans of the movie Serenity hit upon the idea of showing the movie as a charitable event every year in September, the movie’s release month and also when Joss Whedon was born. Universal said they would keep 30 copies in the vault but someone didn’t get the memo and we wound up with 10. It took some co-ordination between the shippers, the central organization, and the various venues to make sure the prints were available when they were needed, especially since weekends were preferred.
Nowadays we just do Blu Ray. Most of the indie houses we use are 4K anyway, and we’ve all seen the film before.