[QUOTE=Dr. Rieux]
Under Suspicion: Portland, Oregon.
[/QUOTE]
Hello, Larry was also set in Portland.
Due South takes place primarily in Chicago (but was filmed in Toronto, IIRC)
JAG takes place primarily in Falls Church, Virginia, but also spends a lot of time in Washington, D.C.
Stargate:SG1 takes place at Cheyenne Mountain, outside of Colorado Springs, and Stargate: Atlantis of course takes place in the fictional city of Atlantis
Walker: Texas Ranger takes place primarily in and around Dallas, TX
The John Larroquette Show took place in St. Louis, MO.
[QUOTE=Cardinal]
Yes, but what state?
[/QUOTE]
North Tacoma.
[QUOTE=Push You Down]
We don’t have Montana yet.
[/QUOTE]
Holding out for CSI: Missoula?
[QUOTE=Krokodil]
Holding out for CSI: Missoula?
[/QUOTE]
A recurring joke amongst my friends here is CSI: College Station.
“Yep, looks like he got drunk and fell down in bottlecap alley. Cause of death: Severe tetanus.”
There’s also CSI: AggieCon, but that’s more of an inside joke amongst the members of the sci-fi club concerning a hypothetical dead hooker. (We never said that any of our jokes were in good taste, or even that good 
)
Neighbours is set in Melbourne (although the actual neighbourhood doesn’t exist in RL, AFAIK) and A Country Practice was set in a fictional town called Wandin Valley, somewhere in NSW.
Shortland Street is set in Auckland, although there’s really no Shortland Street Medical Centre in Auckland.
There’s also no such place as Sun Hill in London, either (from The Bill).
Walmington-on-Sea (from Dad’s Army) doesn’t exist in RL but there was a Stalag 13 (from Hogan’s Heroes) in reality, which was based near the town of Hammelburg- just like the one in the series.
[QUOTE=BrainGlutton]
Are there any major American cities/metro areas where there haven’t been any TV shows set?
[/QUOTE]
Any city in Montana.
[QUOTE=Krokodil]
NYC, but not Manhattan:
All in the Family, Queens
King of Queens, ditto
Grounded for Life, Staten Island
Welcome Back, Kotter Brooklyn
Good Times, Bronx
[/QUOTE]
Good Times is set in Chicago
[QUOTE=Big Bad Voodoo Lou]
Was it ever revealed where Scrubs takes place?
[/QUOTE]
As others have said, the setting is intentionally unspecified, but looks a lot like North Hollywood.
Interesting tidbit, however: Turk’s cell phone number, mentioned on a 4th-season episode, is 916-CALL-TURK. 916 is the area code for Sacramento.
I assume they did this because they simply wanted CALL-TURK in whatever area code the digits were available. At the time, the number connected to a cell phone on the Scrubs set, and was answered by various cast and crew members.
“pensacola wings of gold” was actually filmed in san diego (you could see mountains in the background 
[QUOTE=Push You Down]
They’ve addressed this on the show multiple times. Monica’s apartnent is affordable because it is rent controlled and officially Monica’s grandmother still “lives” there.
[/QUOTE]
But what about Chandler and Joey’s apartment?
Diagnosis Murder is the only one I can think of that changed its setting. It started in Colorado (Denver?), then moved to LA. Funny how so many of the staff moved simultaneously to the west coast to a hospital that happened to be named the same as the one they left in the Rockies.