Barney Fife could take out Ozzie Nelson with a single, perfectly aimed headshot—if he doesn’t drop his one bullet, shoot himself in the foot, or blow away Aunt Bee by mistake.
Hmmmm. Data is a good listener. I wonder if he could help Marvin.
If Barney Fife knew that Ralph Furley was allowing a man to live in one of his apartments with two women, he’d try to nip it in the bud. He’d fail.
Data is fully functional. He could try a variety of ways to improve Marvin’s mood.
Child says in an introduction somewhere about why he created Reacher: “Reacher always wins”. Because he was tired of the ‘ambivalent, conflicted, sensitive’ trend in thriller fiction at the time.
They are very similar, of course: Reacher is sort of Travis without the boat.
I can’t see why they would have reason to fight though. More likely to realize they’re on the same side.. “You take that one, and I’ll take the other… go!” 
Another pairing is John Taylor (Simon R Green’s Nightside series) and Harry Dresden (Jim Butcher’s Dresden files).
I would have liked to see an interaction between those two…
Darrin Stevens II wouldn’t need a spell to take out Darrin Stevens I—just one well-placed knee to that wrecked spine of his or a ‘misplaced’ bottle of pain meds. Endora wouldn’t lift a wand to help, just sip her martini and whisper, “Finally.”
Also remember that a horse is worth 2 or 3 horsepower. Apparently, Watt’s horses were slackers.
What about friend groups facing off in gang fights? Who has the edge in Friends vs. How I Met Your Mother? or Happy Endings vs. New Girl*? And who’s going to go up against the Always Sunny gang? The brothers in Malcolm in the Middle, maybe?
I think I might give the brothers the edge against any of the others because they’re so reckless. You have to take Frank Reynolds’s gun away from him, though. If you can.
SNL had the Brady Bunch take on the Partridge Family.
They couldn’t talk either. Both Mr. Ed and the car could.
Are you kidding? Marshall Eriksen can take on all the Friends by himself - the dude’s scary. And that’s without Robin and her guns in the mix.
And Lily! She’s scary
Seriously, Ted is as useless as one of the Friends, but Marshall, Lily and Robin are way scary. Robin has fought of a wolf with a knife. Marshall his used to wrestling his even larger brothers. Lily is the native New Yorker that teaches Kindergarten. She has speed and ferocity. Barney, may not be too useful.
Maleficent (Disney’s version) vs the Wicked Witch of the West - who would out-spell the other? One can turn herself into a dragon, the other has flying monkeys. No contest.
How about Anton Chigurh from No Country For Old Men versus Big Chris from Lock Stock and Two Smoking Barrels? I think Anton Chigurh has that one hands down. Cheeky cockney hard man stands no chance against well, Anton Chigurh
Haven’t seen either, so I get no vote
I never got the impression the Addams clanwere superhuman beyond Fester’s light bulb trick. Herman is a Frankenstein’s Monster. Grampa is a vampire. They’d handle the Addams Family without breaking a sweat.
But Monica is freakishly strong.
Thing would pin the Munsters down one by one, while Cousin Itt smothered them under a tsunami of hair, and Lurch pounded out The Death March on the harpsichord.
Remember, it’s not just stronger, it’s also smarter and more clever. Barney would have skills to bring to the table.
Ted, yeah, you’re right, pretty useless.
The Seinfeld gang, of course. Sociopaths vs. sociopaths.
Jerry might even temporarily form a strategic truce with Newman and let him join the friend group temporarily, since Newman is a devious bastard.