An earlier thread on this subject:
Ninety-Six, South Carolina is not too far from where I live.
For the Marines in the house:
Eastbound from Ash Fork, AZ on I-40 headed towards Flagstaff, one will pass a sign for “Devil Dog Rd”.
Tripler
And if that weren’t enough, someone slapped a globe and anchor sticker on the sign. 
My Dad was born in Medicine Hat, Alberta.
Here in British Columbia we have Spuzzum, Squamish, Coquitlam, Matsqui Tswassen and Lillooet. As you can see, the settlers didn’t bother to change things much!
Pitt Meadows gets a fair bit of, um, modification…(just sub “s” for “t”).
In the LA area there’s Rancho Cucamonga, Tujunga, La Canada (cahn-YAH-da), etc.
My mother was born in a small Florida town called Wewahitchka. There is also a Frostproof and a Kissimmee in Florida.
dutchboy208, “Sault Ste. Marie” is slightly-mangled French for “The Rapids of Saint Mary”. (Ste. = Sainte.) These rapids are on the St. Mary’s River between Lake Superior and Lake Huron. The Canada/US border runs down the middle of the river. Yes, a succession of canals have been built there, on both side of the border, but there is also a city on either side, named Sault Ste. Marie. This is usually shortened in colloquial speech to “The Soo”, and often written on letters as “S. S. Marie”.
The Canadian city has a population of around 75 000; the US city is smaller. Both cities started as settlements associated with the canals, I believe. On the Canadian side, there is a steel mill (currently in trouble), a tourist train into the northlands, and the usual facilities associated with a border town.
Sault Ste. Marie, Ontario, is also the regional service centre for a vast area of northern Ontario, so it has a greater variety of things than one might expect from a place its size: two colleges, a larger-than-expected mall, the headquarters of the Ontario Lottery and Gaming Corporation (thanks to a policy of government decentralisation), and the Ontario Bushplane Museum, for instance. It is the home town of one of Canada’s astronauts, Roberta Bondar.
How do I know all this? My sister lives there. 
Oregon has Boring and Drain and Sisters.
We have a lot of Native names here, including Tititlik.
My Fave?
Buttzville, NJ!
There is actually a hot dog joint called “Hot Dog Johnny’s” in Buttzville, and you can buy a shirt that says
Hot Dog Johnny’s
Buttzville, NJ
Seems vaguely naughty…
There’s also “Ong’s Hat, NJ”, and “Mount Misery, NJ” both of which are in the Pine Barrens, where the tallest thing around is the “Forked River Mountains” which tower 182 feet above sea level, and are located in “Forked River, NJ” (Pronounced like the word “fork” and then the name “ed”). In Southern NJ, there is a “Nummytown” and a “Miami Beach” as well. There is a “Sim Place, NJ” as well, which is also in the Pine Barrens. In North Jersey, there is a Ho-Ho-Kus, but I don’t know why…
Didn’t Johnny Knoxville find a town called ‘mycock’ or something?
My dad is from Ducktown, TN and lived for a while in Turtletown, TN.
I live just up the road from Uncertain, Texas.
For sheer unpronouncability there’s the sister cities of Nacogdoches, TX and Natchitoches, LA.
I don’t get what’s so funny about Voorhees, NJ. I used to live near Voorheesville, NY…
Who can forget:
Joe, Montana
Bald Butte, Saskatchewan (only funny when mispronounced)
Conception Bay, Newfoundland
I heard on CBC One once that there was an Athol, Ontario, pronounced Athhole.
Yeah! Johnny Knoxsville visited “Myanus” I do believe.
I’m quite fond of Conception Junction, Missouri
It just sounds like fun.
About 8 miles down a crappily paved road from my town is Earlton. Yeah, its as crappy as it sounds. It has one store and no restaurants and about 4 streets.
Yep. Ho-Ho-Kus still exists. More of a village between Waldwick and Ridgewood, but it’s still there.
Tripler
I’m from Ramsey, just up Franklin Tpke.
How did I know home sweet home would get mentioned here.
Though featherlou got most of the Saskatchewan ones, I’ll add in Livelong, Love, and Cando to the list. And of course Regina, famously mocked by David Letterman, which rhymes uncomfortably with a part of the female anatomy.
I grew up not far from Knockemstiff, Ohio.
On a long road trip last year, I couldn’t pass by this sign without taking a photo.
A small settlement in West Virginia officially changed its name from Mole Hill to Mountain as a stunt for a radio program.
Belchertown is a town in Massachusetts.
Bumpass is a village in Virginia.
Chicken Strip is an airport in California.
Lower Fannys Hole is an unpopulated place in Idaho.
Fucking is a town in Austria
Nobody’s mentioned Gnaw Bone, IN ? I used to commute through it (with a beer in my hand - necessary to maintain mental health in that part of the world…