Holy crap, this one may not be possible. Unless glowy is a word. It’s not in http://www.dictionary.com or http://www.m-w.com.
Oh yes it is…(Sprints back from place where he was crying)
Shame
shams
slams
slims
slime
slide
glide
glade
glare
glore
Glory
“glore” is questionable, but a word according to http://www.dictionary.com.
Nice --> Jerk
Nice --> Jerk
Nice
dice
dire
dare
pare
part
pert
perk
Jerk
Try God --> Sex?
God
got
get
set
sex
flame -> steam
flame > steam
flame
flams
slams
spams
spans
spins
shins
shies
spies
spied
speed
steed
stead
steam
word > game ???
word
ward
ware
dare
dame
game
ooops. too easy
evil > good
I bet this one’s tricky.
Maybe impossible.
Evil -> Good:
evil
emil (had to use a name here…)
emir
amir (“amir” and “emir” are both variants of the same word)
amid
arid
grid
grip
trip
trap
tram
dram
drat
brat
boat
goat
goad
good
Assuming the above counts as a solution, try:
moral -> whore (untested)
Blue -> Pink
blue
slue (variant of slew [variant of slough])
slut
slot
plot
piot (THE magpie)
pint
pink
[sub]All words checked on http://www.dictionary.com[/sub]
Geez…why must I use such stupid words? How did you do it, JBERGES?
And, um, keep working on moral -> whore
In 4 seconds, here’s what I got
Moral
Coral
Uh
Uh
Uh
Whole
Whore
Go me! 
::Pumps fists into air::
moral > whore
moral
modal
model
modes
codes
cores
corks
cocks
socks
soaks
soars
scars
scare
share
shale
whale
whole
whore
soft > hard…untested and probably easy but it’s late and I don’t want to do another 
soft
sort
fort
fart
hart
hard
How about…
True > Love
true
tree
free
fret
feet
fees
lees
lets
lots
lops
lope
love
Okay, that was too easy. The floor is open.
Um, for the sake of keeping the game going:
Sale -> Buys
Bart -> Good
Death -> Alive
Simpson, eh?
Bart
barn
burn
bury
busy
bust
must
most
molt
mold
gold
good
Sorry… I was watching the new episode of The Simpsons at the time…yep…I’m the kind of loser who has seen every single episode.
Sale --> Buys
Sale
salt
malt
mast
mass
maps
caps
cays
Bays
Buys