I’d appeal to my friend’s desire to protect his daughters (while pointing the AK at his head and reminding him that I am a much better shot than he is). Then I’d destroy the virus. Any suitably hot furnace would do. Oh, and collect the reward for Osama. I’d then use the money to erect a Jewish deli on the site of his death.
But it would only stay there for 20 minutes…
So me and my buddy now have $50 Million, and a Doomsday Virus. Cool. All your base are belong to us.
I guess I’d make a grab for the gun (assuming that we didn’t empty the thing into Osama as I probably would have had I been in this situation.) If my “friend” couldn’t be persuaded at gunpoint to destroy the vial, I’d shoot to wound and then burn the thing myself.
That or kill this so-called “friend” who has served his purpose and keep the vial for myself in my secret underground base as I schemed a way to turn it’s power to my own ends in a bid for global domination. Mwahahahahahaha!
Might I enquire what inspired this scenario? I’d wager this doesn’t come directly out of first hand experience.
Since my best friend is not a whacked out Muslim, I can’t see why I’d get very upset about him holding onto the vial for a bit.
I’d suggest that we unwind after a stressful day with a few drinks at the bar. I’d get him drunk and take the vial. And probably his wallet, too, for good measure.
So, what page of the Choose Your Own Al Qaeda Adventure book do I turn to now?
Why again I am in the desert just wandering around.
Am I on peyote or something?
Nah, you’re just Jewish! 
Or a guy, who will never ask for directions.
I know my friend well enough to be able to say confidently that all I’d have to do is offer to buy her an iced coffee at the first place we see if she’ll let me hold the vial instead.
Then I guess I’d throw the vial into some liquid hot magma whenever I have time.
Well, with any of my best friends, I would tap into their competitive side to get them to hand over or destroy the vial. “I know you couldn’t destroy that vial right now…thats why your holding onto it. You aren’t smart enough to destroy the vial are you?” This would be followed by, “The hell I’m not!” And throwing the vial into a volcano or something. I assume this scenario all takes place somewhere near a volcano.
If that didn’t work, I would quickly remove osama’s head and offer to split the $50 mil if they destroyed the vial right now. Hopefully the love of money would be enough to make them destroy the vial.
RTA pretty much nailed it. When I saw LOTR, I was desperately trying to like the film until the scene where the two guys are standing in the volcano, and the one guy decides to keep the ring and his buddy just let’s him walk out of there. At that point, I wanted to stand up in the theater and scream, “What are you? Fucking nuts? Kill the bastard, goddamn it!” After that, I just gave into the hate.
Why is bin Laden acting like a James Bond villain? How does he benefit from telling you his plan rather than just killing you and your buddy?
That said, I’d probably kill him given the chance, given that (a) I’m obviously in danger from his plans, (b) he’s a competing super-villain ;), and © he’s an embarrassment to the super-villain guild. I mean, he’s MONOLOGUING!
My friend and I, both consumate germophobes, would pour anti-baterial hand cleaner into the vial. Then lysol* the mofo with absolute maniacal fervor.
*I’m pretty certain that what ever this Terrible Germ is falls under the .1 factor of Lysol’s non killing power, as provided for by the Lawyers.
I’d move to Copenhagen and start a garage band named “You and Your Best Friend Find Osama”.
Oh and I’ll hold the world ransom with the vial if the first record doesn’t go platinum.
RIAA, eat your heart out. No really, here’s a fork.
wait.
What kind of music are you going to make? Emo Goth rockabilly? Or Euro Techno Dance Opera Swing? I gots to know!
I was thinking a a Bee Gees tribute band sung in the style of Alanis Morrisette meets Tiny Tim. With accordions.
What good is anti-bacterial hand-cleaner against a virus?
I don’t have any friends.
Accordions are always good!
Kinda like using prayer for a cure, I guess. It makes the user feel better.
/one ticket.