Anti-cortisol diet pills: anything to it?

Ordinarily my chances of believing an infomercial hawking the latest snake-oil remedy would be zero. But I couldn’t help but be struck by how closely the symptoms of “excessive cortisol” match my life. I am overweight, a naturally high-stress person, a very light sleeper, very groggy mornings, poor energy, eating as a response to stress, extremely sensitive to sugar and carb induced mood swings; the list goes on.

Does the mainstream medical establishment think cortisol level control is something some people really need? No, I don’t expect a pill to do all the work of losing weight, but is it a useful aid in coping with stress?

Very high cortisol levels can have a bad effect on your physique, but very low cortisol levels can kill you. It’s a pretty important hormone, so I’d err on the side of not fucking around with something I don’t totally understand.

No. Cortisol is the miracle steroid (the SAID from which today’s NSAIDS get their name) that was used to combat arthritis back in the 40’s and 50’s. When it turned out that too much cortisol led to depression and suicide among patients, doctors cut back on its use. Numerous reports document a rise in corticosteroids during depression, and a fall in DHEA levels, but AFAIK, no one has ever worked out the causal relationships. Messing with steroids, or steroid levels, when you don’t have good clinical reasons to do so is foolish. Here’s a couple of examples of good reasons to mess with cortisol:
Addison’s disease
Cushing’s syndrome

Also, the lists of symptoms associated with those miracle pills advertised on the radio and late-night TV are (intentionally, IMO) vague and broadly applicable.

“Do you sometimes wish you could sleep in instead of going to work? Do you wish you had the motivation to eat less and exercise more? Do you feel tired just before you go to bed, and still feel tired in the morning before breakfast? Do you feel like there’s a part of you that you show the world, and a part you keep to yourself? Is there someone important in your life whose name starts with S, or maybe F?”

Don’t get too excited just because you fit the list.

Lumpy,

Are you asking about Relacor?

If you’re talking about Cortislim:

I was asked to research this recently. I won’t go into the physiology of cortisol micro-regulation because it’s complicated, and in the end irrelevant. If you check the company’s website for the actual ingredients of the pill, you’ll find that have a dubious relation to cortisol levels to begin with, according to what little serious scientific literature there is on them.

Dr. [Shawn] Talbott seems to be a properly credentialed researcher, whatever you think of his theories (I have not read his books, but according to my literature searches, he has never he has not published any research in humans related to the assertions in his books*, but his relation to the Cortislim product is unclear. It is interesting that Dr. Talbott’s first name was not even revealed until the most recent series of ads, which made it harder to check his reasearch

“Dr.” Greg Cynaumon, the self-admitted non-expert “spokesman” (according to the infomercials and many press releases you’ll find by googling his name) or “co-creator of Cortislim” (according to his current website, reportedly holds a “diploma mill” PhD in psychology, and has been involved in two possible major scams in the past decade (a nationally advertised “miraculous” educational phonics game ca 1996, and more recently, an employment “scam”(?) that has been the target of government action and civil suits)

I won’t assert that that all the allegations are true. The few I verified with, e.g., CA state licensing boards and Dissertations abstracts, seemed to be accurate, but I am neither a professional investigator nor a lawyer. Here’s a site outlining the allegations. Check it out and decide for yourself.

My own background, in medicine and molecular biology, made me highly skeptical of the product. Note that it does not claim to control cortisol, per se, it simply makes nonspecific claims to somehow “optimize” various parameters if they are already normal! The {url=http://www.cortislim.com/faq.htm]Cortislim website implies that it (e.g.) stabilizes levels of certain hormones or blood sugar, but it never actually says this, or speciefies any verifiable effect.

This I can say: one documented effect of one major Cortislim ingredient is a mild calming effect, and possibly greater ease of getting to sleep. In related support groups and user bulletin boards, one often finds users who report these effects, even if they don’t observe any other. Many find this “worth the price of admission”, but this is not what Cortislim primarily promises.

I should note that an unregulated “herbal” product does not in any way indicate a "gentler"treatment with “fewer side effects”. When the active chemicals in the herb are characterized, extracted and provided at a regulated strength and purity, it becomes an “medicine” and hence “harsh and unbalancing” in the eyes of some, but at least it, its effects, side effects and any risk factors are far better known.

This is not medical advice.

Ah, yet another Wonder Pill who’s ingredients turn out to be the usual medley of herbal remedies. Glad I didn’t waste my money. Thanx all!

Lumpy, it sounds like you’d be much better off trying to stabilize your insulin levels first. That works wonders. Corgard and other beta-blockers are good for managing that “fight or flight” stress/anger and is particularly good for performance anxiety. As cheesy as the title sounds, the “diet” is actually quite good and easy to execute:

http://www.amazon.com/exec/obidos/tg/detail/-/0345419987/qid=1085574892/sr=8-1/ref=sr_8_xs_ap_i1_xgl14/104-4543138-5494304?v=glance&s=books&n=507846

It’s the only way of eating I would consider and while I lost all the weight I want to, I continue to use it because of the benefits to stress, depression, and energy levels. I’ve taken Corgard before for stress from taking Adderall. There is a bit of a rebound effect.