[QUOTE=Podkayne]
What’s the best knitting podcast? Some fiction would not go amiss . . . offbeat fantasy, sci-fi, experimental stuff—have you discovered any diamonds in the rough?
[/QUOTE]
Cast On, with Brenda Dayne is generally regarded as one of the best knitting podcasts. Brenda has a great voice for podcasting, and an interesting way of talking about knitting. She’s on hiatus right now, I think, but is supposed to be back soon.
For science-fiction stories, I really like Escape Pod. Steve Eley picks some really good stories, and the podcast is well-done. They have two different streams: one contains just the stories that are Good for the Whole Family and the other stream contains those stories PLUS stories with more adult themes.
Spaceship Radio rebroadcasts old SF radio dramas. Sometimes their sound quality is a little funky, but it’s fun to hear the old shows.
Michael R. Menenga and Evo Terra have a couple of good shows:
Dragon Page Cover to Cover focuses on written SF. They have interviews with authors and other features. Their Slice of Sci-Fi podcast focuses on sci-fi in movies and on tv. The hosts are fun to listen to. They also podcast Wingin’ It, which is all about the beer, and can get raunchy occasionally. Be warned.
The Kick-Ass Mystic Ninjas* don’t podcast nearly often enough for me. They concentrate on more vintage sf. Their latest show was on Theodore Sturgeon’s book More Than Human. Great geeky fun.
I also like Jack Mangan’s Deadpan Podcast. Not just about sci-fi.
I also subscribe to the Librivox podcast. They just finished reading Pride and Prejudice, and are now on Sarah Orne Jewett’s book The Country of the Pointed Firs. Good stuff.
I have a few more I listen to regularly, but these are the ones I look forward to. Except I had a little disagreement with Brenda Dayne, and haven’t quite felt the same about her since.
Why yes, I listen to lots of podcasts. Why do you ask? 
*IMHO, Best. Name. EVAH.