This thread is a fascinating read.
First, I don’t know Una and have no particular knowledge about her medical condition. Back in my university days I did work with issues of sexual differentiation in a research setting. I know issues such as are under discussion in this thread often bring up some questions of a “How did that happen developmentally” nature. I do not want to hijack this thread so will spoiler a little basic background reading on the science type stuff for any who may be interested.
For those looking for a little more background reading the Wikipedia article on Sexual differentiation is an ok starting point. Some key points:
[ul][li]In human development, the default path is for a fetus to develop as female.[/li][li]There are a lot of signalling hormones which must be properly received by specific receptor molecules to guide the differentiation process to make a fetus develop as male.[/li][li]There is some tissue that is part of the mesothelial peritoneum (a membrane that lines the abdominal organs) in the developing fetus. This same tissue can develop into ovaries or testes, depending on the aforementioned hormones and receptors.[/li][li]Genetic changes to any of several genes could disrupt the typical differentiation process.[/li][li]Depending on exactly what is disrupted and where in the differentiation pathway the effect is felt, there are numerous Disorders of sexual development.[/li][/ul]
There are numerous possible variations in physical appearance of the primary and secondary sexual characteristics. We are still learning about the sexual differentiation of the brain which strongly affects gender identity. Differentiation of the brain occurs independently of the sexual differentiation of the primary and secondary sexual characteristics.
Net result:
a person may have a gender identity that does not match how his/her body differentiated (male appearance but identifies as female or vice versa);
a person may have external genitalia typical of one gender but secondary sexual characteristics typical of the other gender;
a person may have external genitalia which are not unambiguously male or female;
a person may have primary and secondary sexual development typical of one gender but have a genetic karotype typical of the other gender (XX male or XY female);
and any such person may self-identify (have a gender identity) as female, male, both, or neither;
and regardless of gender identity, any such person may be sexually attracted to males, females, both, or neither.