Civil War. Hands down.
A close second goes to Sweet Child O’Mine though. But Civil War is their best song.
I’m sure you all agree with me so let me know!
“Mr Brownstone” is my pick.
My favorite is “Dead Horse”.
Well, I came in here to answer, but Cubsfan stole my answers for the OP.
“One In A Million” is a great song.
Too bad he has to ruin it with those lyrics. . .either that or I missed the satirical sociological points that axl was trying to make with that tune.
I won’t argue too much with Civil War – I’m man enough to admit I even like some of their other “ballad” type stuff like “November Rain”.
Sweet Child of Mine, no doubt. The line “She got eyes of the bluest skies, as if they thought of rain” is awesome.
My sentiments precisely - I like to think it’s an over-ironic satire on bigotry - but I just can’t believe it. A pity, because otherwise it’s my favourite…
My vote goes to You Could Be Mine. Kicks ass! 
The acoustic version of “You’re Crazy” on Lies is my favorite.
I’m gonna be the heretic here and say Live and Let Die.
Man, I’d kind of forgotten how great GnR were in their day. When I saw the OP, about 10 songs popped up.
Once I got kind of sick of the released single songs on Appetite, I was always partial to “Rocket Queen”.
Shame they did the rock star flameout so quickly.
Absolutely. No contest, not even close.
Really hard to pick just one, but I like “It’s So Easy” because it rocks so fucking hard.
I also like their cover of “Dead Flowers” on the bootleg Unplugged album.
Hard to pick!
Based on Staying Power and Song Writing: Sweet Child 'O Mine
Based on my personal taste: Mr. Brownstone (Welcome to the Jungle, close 2nd)
Based on later work after the venerable Appetite for Destruction: Civil War (no contest)
Best Acoustic: Patience
Their Best Cover: Sympathy For The Devil
My Favorite Non-Favorite: It’s So Easy
I have to go with Mr Brownstone. Some of the others I will flip from to try and find something I haven’t hears a million times. I always crank (no pun intended) up Mr Brownstone.
Or anything off Chinese Democracy.
“Civil War” and their cover of “Knockin’ on Heaven’s Door”.
4 way tie
Rocket Queen
Mr Brownstone
Night Train
and
Dead Horse
Why’d you just…fuck off! Huh!
That line always made that song for me.
It feeds the rich while it buries the poor…
Agree with OP, although Mr. Brownstone is a lovely little ditty.
“You Could Be Mine” & “Mr. Brownstone” are tied for my favorite. “Night Train” is my ringtone, though - which was pretty amusing when my phone rang during an AA meeting.