The one who drowned her kids in the bathtub. I get she was crazy, but one of the few people who I could gladly see being put to death.
Edit - Andrea Yates
Another vote for Hanoi Jane, and one for Hillary Clinton.
Enough politicians and criminals. We need celebrities.
Roseanne Barr
Miley Cyrus
Lady Gaga
Janeane Garofalo
Anne Hathaway
Katherine Heigl
Paris Hilton
Kim Kardashian
Jennifer Lopez
Rosie O’Donnell
Gwyneth Paltrow
Kristen Stewart
Taylor Swift
I think we’ll find that the wife of every Democratic (male, or maybe someday, lesbian) President from here on out becomes an honorary target for scorn, simply by association with whoever the current “worst President we’ve ever had” happens to be. And to be fair to the right wing, Ms. Obama is awfully uppity. Keeps opening her mouth and saying stuff, instead of standing silently like a First Lady is supposed to do.
Of course, Mr. Mortiss may have a specific, concrete and completely justifiable reason for hating Michelle Obama, in which case we should all prepare to be enlightened.
Okay, I’m going to admit I don’t know who Heigl is, but all the others, yeah. I can endorse this.
Yoko Ono? Why? Because she protested against the Vietnam War?
Since it’s limited to living women, I’ll pick Ann Coulter. All she does is troll.
Living or dead, Ayn Rand. Smug and wrong are a really unappealing combination.
Oooh, that bitch!
In fairness, somebody just nominated old lady Bush, too.
As far as I know, Michelle Obama hasn’t said things like New Orleans refugees (from Katrina) being housed in the Houston Astrodome were “underprivileged anyway, so this is working very well for them.”
Or of the war in Iraq: “Why should we hear about body bags and deaths? It’s not relevant. So why should I waste my beautiful mind on something like that?”
Oooops. I missed the “alive” part, so change my vote to murderous McCarthy. Bitch has single handedly set vaccinations back years.
What exactly is there to hate about Michelle Obama? Has she ever said or done anything even remotely controversial?
As we’re rolling over to a new page (the way I have mine set up anyway) I’m starting to think we need at least two polls, probably three.
- Celebrities (non-political)
- Political figures
- “In The News” Others
Maybe even more if the categories start filling up the way the first three have.
We may even need to have a DEAD poll!
Altogether there have been over 50 names so far, many of them dead, so the multiple poll idea seems needed for the sake of not putting all the despicable ladies in one stack.
With that enhancement in mind, if you want to rethink your own submissions and put them in categories, that would help get the polls closer to ready to post.
For what it may be worth, I don’t have any problem at all with somebody else going ahead with some subset of these names in a new thread (or more). It’s gotten bigger already than I had hoped for! 
The food industry hates her because she wants people to eat healthy.
Hey, Madeline Albright is still alive, right? Put her on the list.
I think Fonda has got to be a easy number one.
1.) My fifth grade teacher Ms. Ode, but she’s probably dead, so…
2.) Oprah
Maybe because she (supposedly) helped break up the Beatles?
Gwyneth Paltrow seems to get a lot of hate, as far as celebrities are concerned.
I was trying to think of a political figure who hasn’t been mentioned, and the best I could come up with is Winnie Mandela. Though I think for most people her role in ending apartheid outshines the crimes she’s been accused of.
- least personal favorite, not most despicable woman in the world.
- living, not dead.
Mine would be my first wife, who forged my name onto her child’s birth certificate, o left me for a wandering minstrel, made it impossible for me to divorce her because they traveled all over Europe making it impossible to serve divorce papers, left the minstrel and came back without letting me know, then went on welfare for about a year and a half in the state of Washington…who then billed me for every penny they gave her and her child for food, rent support and welfare and medical costs.
I will second Nancy Grace, and add Lorena Bobbit.
It took 55 posts to mention Oprah “the universe has plans for you” Winfrey?
I’d been waiting patiently for Oprah’s name to appear before posting this summary, which I hope is all-inclusive of names through Post # 59:
Please provide needed corrections (including putting them in the right category) and please keep adding to the list(s)!
===================================
Straight Dope Message Board > Main > In My Humble Opinion (IMHO)
Candidates for Least Favorite Female Human Being
*** Politics / Political Commentary
Madeline Albright
Michelle Bachman
Jan Brewer
Barbara Bush (the old woman, not her granddaughter)
Hillary Clinton
Ann Coulter
Stephanie Cutter
Nancy Grace
Winnie Mandela
Michelle Obama
Sarah Palin
Nancy Pelosi
Phyllis Schlafly
Lea Thompson (TV journalist)
$$$ Entertainment
Roseanne Barr
Rhonda Byrne (author)
Miley Cyrus
Jane Fonda
Lady Gaga
Janeane Garofalo
Anne Hathaway
Katherine Heigl
Paris Hilton
Kim Kardashian
Jean Kasem (Casey Kasem’s wife)
%%% Kyle’s mom
Lindsay Lohan
Jennifer Lopez
Jenny McCarthy
Heather Mills McCartney
Rosie O’Donnell
Yoko Ono
Gwyneth Paltrow
Kristen Stewart
V. Stiviano
Taylor Swift
Oprah Winfrey
“In The News”
Casey Anthony
Lorena Bobbitt
Charlene Gallego
Karla Homolka
Nadya (Octomom) Suleman
Andrea Yates
+++ DEAD +++
Tammy Faye Baker – dead
Elizabeth Bathory – dead
Irma Grese – dead
Leona Helmsley – Dead, yes, but likely the biggest bitch in hell.
Myra Hindley – dead
Ilse Koch – dead
Delphine LaLaurie – dead
Jiang_Qing – dead
Ayn Rand – dead
Margaret Thatcher – dead
Aileen Wuornos – dead
===================================
My apologies to those mentioning family members (past and present), teachers, and others unlikely to get any votes in a poll other than by the one involved.