Yeah, but almost all of them have a beloved celebrity at the center of it. My mom is one of the world’s biggest Two and Half Men fans and even she thinks Sheen is a douchebag.
Beyond that, most of these stories end with the subject being redeemed in the eyes of his/her loved ones. Do you see that happening with Sheen?
Second.
There isn’t any other actor out there who can process Charlie Sheen’s brain.
Jon Cryer
I think he’d be a brilliant choice. His performance in Tron: Legacy showed that Michael Sheen can strut and leer with the best of them. He has an American accent in Unthinkable.
“Hey, Bro! Remember when we were little and you used to repeat everything I said and drive me crazy? Guess what my next project is?” 
Both Gary Busey and Christian Bale are inspired choices. I’d go with either of them.
Of course, Emilio would probably be funnier.
Paul Reubens! This flash of inspiration came to me after reading “Cops are inside the house right now, searching for firearms and ammunition. […] Charlie and others in the house are at the dining room table eating hamburgers,” at TMZ. It’s a natural!
A “Top of the World, Ma!” type ending could work, too.
Charlie hoovers up ten pounds of cocaine, grabs a grenade launcher, screams, “Say hello to my leetle friend!”, and goes out in a hail of gunfire? I can see that.
He’s reminding me of Lonesome Rhodes a bit lately…
Gary Busey is a hundred years old. You need someone younger than Sheen.
This could make a successful movie. Give it ten years and you can just fill the screenplay with lies wherever the story needs it.
The same people who are watching this.
Oh, I wasn’t thinking about it from a purely physical stand point. Just who’d be crazy enough.