Meta answer: The point of Doomsday is that he can kill heroes. He destroys plot armor. He would murder as many Marvel heroes as necessary to prove that point.
So, Squirrel Girl could stop Doomsday. AND vex him.
End of thread. Sorry.
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But since this is too fun of a thread, to just end, I was thinking that the DC heroes basically tried…
…hitting Doomsday, then hitting him hard, then harder, then reeeeally hard, and then Superman hit him super-hard.
But the Marvel bullpen has geniuses.
So I’m betting Reed Richards, Tony Stark and Bruce Banner could come up with The Ultimate 4D Chess Scientific Solution, while Dr. Strange and the Scarlet Witch worked on a magical one. And add in some Cosmic Shit from the Silver Surfer, Adam Warlock, Captain Marvel, the Shi’ar, Thor and Loki and Odin … and, heck, One•Above•All, Marvel’s ultimate cheat code (yeah, he’s God).
Oh, you still want to try violence? Hey, Galactus, over here!
Like Hulk, Doomsday can’t fly and had no projection powers. At least in his initial appearance. Any teleporter or powerful telekinitic could just put him in outer space.
IIRC (been a long time now) didn’t Superman (or someone) toss Doomsday to the end of time to get him out of the way? I completely forget how he managed it except that he had a gizmo to do it (magic or science I’m not sure).
Doomsday’s main power is the ability to return back to life with complete immunity to whatever killed him. So any brute force attempt is doomed to fail eventually. Any physical hero like Hulk would be useless. Getting him safely out of the way without killing him is the only option, Dr. Strange is probably the best one for the job.
The Infinity Gauntlet was the first series, followed by Infinity War and concluded with the Infinity Crusade.
Galactus was in the Infinity Gauntlet series as one of the opponents of Thanos, since he could sense that Thanos was creating a power imbalance in the universe.
Much later, Galactus sought to use the Infinity Stones himself to change into a being that no longer had to eat worlds to survive. He hated being the destroyer he was forced into. It didn’t work out well though.