We’ve all seen movie quotes up and down into the sixth degree, but does anyone have any GAME quotes that fit the bill of a great quote? Specifically thinking video or PC games here 
My favourite quote is probably from Psychonauts:
Either that, or Grim Fandango (the game from 1998 where you’re playing the assistant Grim Reaper . . . ah, good old times!)
The City of Heroes developer team loves to put funny stuff in the NPC’s speech bubbles. The best one, I think, is when your character is investigating an impending arms deal between the Nemesis Army (a group of very Old-World types–the leader is more than 200 years old) and the Freakshow (a modern street gang that likes to install lots of bionic implants in themselves). You are approaching a corner and the two negotiators’ voices reach you.
The very straightlaced Nemesis guy is saying to the Freakshow punk, “I assure you, my good man, that Nemesis is most definitely ‘down with the street.’ Word up, my homie, as it were.”
You come around the corner, the Freakshow says, “We should kill this hero.” The Nemesis negotiator says, “I most heartily concur. A’ight.”
I love clicking on Warcraft characters until they start saying silly things. My favorite was the Demon Hunter:
“Darkness called me…! But I was on the phone, so I missed him. I tried to star 69 him, but he wouldn’t answer. I said: PICK UP THE PHONE, DARKNESS! But he ignored me. Darkness must have been screening his calls.”
And then the Banshee:
“I hate you, I HATE YOU!! … Call me!”
Vampire:Bloodlines had al sorts of strange things hidden in the dialogue, but if you played through the game as a malkavian (=nuttier than a bag of squirrels going round and round in a washing maschine), the dialogue wen from strange to shakespeare-on-speed. However, the most interresting bits was where you were allowed to “project” your madness to other people. Meaning that the correct way to get an anoying hospital security guard to hand over his keys is to say:
I AM A KEYCHAIN. FEED ME.
Another from Grim Fandango, one of the few genuine Laugh-out-loud moments I’ve had. Some evidence vaguely implicates a fat man as the main bad guy.
Salvatore, the head revolutionary character, looks into the camera, although he’s actually speaking to someone else ‘Who is this fat man and how does he fit into this whole sinister puzzle?’
Doesn’t sound much written down, but something about how it was delivered sent me into hysterics.
STRAGO: “You spoony bard!”
Isn’t that FuSoYa from 4 rather than Strago from 6?
Ruby, from Eternal Blue: “White knight Leo, 35 years old and never had a girlfriend. People are starting to talk.”
“C’mon Lucia! You’re placing true love on the altar of trust and spitting on it!”
Sven T. Uncommon, from Popful Mail (these are better for the bad Austrian accent than the lines): “Oh, the little infant has a brain. How impressive. When did you graduate from potty school?”
“I could almost cry. But then I would have to eat quiche.”
Gaw, from the same game: “You’re a penguin. I could roast you with my spit.”
“We have a visitor. Stay a while. Stay…FOREVER!!!”
Impossible Mission, Commodore 64.
“I picked up the reflector from the theodolite. It was bright and shiny and…I like bright shiny things.” George Stobbart, from Broken Sword: The Smoking Mirror.
Note on th OP: both Grim Fandango and Psychonaughts are video games by Tim Schafer and much of the same team, too.
Psychonauts has so many great lines, it’ll be impossible to list them all. So, here’s a small selection of some favorites (some of which, I must admit, are way funnier in context):
Raz: So, is this the part where you give me some long speech about losing control before I get my merit badge?
Sasha: No. Here’s your badge. Let us never speak of this again.
Agent Cruller: Are you ready?
(the game gives you a choice of “Yes!” or “No, not yet.” If you pick ‘no’, Agent Cruller slaps you across the face.)
Agent Cruller: How about now? (same choice again)
Peasant: I’m ready to die for my ruler!
Raz: You might not die!
Peasant: Hey, he’s a great leader, but, he’s still Fred.
Raz: (on discovering the identity of The Phantom) I totally guessed that!
Bird: Nuh uh! You said it was Becky! (Raz swats the bird away)
Lungfishopolis News: The Navy is responding with what they’re most famous for: airplanes!
J.T.: The Deadly Nelson sounds pretty dangerous
Mikhail: Hm. Could use Deadly Half Nelson. Is less deadly than Deadly Nelson.
J.T.: How much less?
Mikhail: Half.
And there was that whole exchange between Raz and Dragon about what that smell was. “It’s the smell of FEAR!” “No, I’m talking about an actual smell. It’s more like rotten eggs…”
“All your base are belong to us”
From Baldur’s Gate 2, the characters Minsc, Jan Jansen and Korgan have some hilarious dialogues. A sampling:
Jan interacts with Keldorn the paladin:
Keldorn: One must maintain constant disciple and remember the four principles of virtue … that is my motto and everlasting burden.
Jan: Virtue, eh knighty?
Keldorn: Indeed, little one. ‘Tis not virtuous to refer to me as ‘knighty’.
Jan: Another human with his shorts in a knot. But I digress. Anyway, Keldy, my mother wrote a book on virtue.
Keldorn: Did she?
Jan: Oh yes, a book on the virtues of erotic love. “Sins of the Flesh Golem”, it was called. Excellent sales in the paladin’s spouse market.
Keldorn: A wholly inappropriate jest, Jan. You should be ashamed.
Jan: It is no jest. I’ll send you a copy, if your wife does not already have one.
Keldorn: Never speak of my wife, gnome. Your lack of respect is appalling.
Jan: Ah, now I see. One of THOSE.
Keldorn: It is not your place to judge my affairs. You must learn to respect your leaders.
Jan: I do respect my leaders. This has nothing to do with them. This reminds me of the chapter where the paladin first makes passionate love to the flesh golem. What a beautiful scene
…
Keldorn: Begone, gnome, lest my honor demand that I perform which acts that you shall regret.
Jan: “Fleshy, honey,” the paladin said. “Yes, baby?” the golem said …
And here are some Korgan quotes:
encouraging Jan to not bother with a story:
Jan: Korgy old pal, have I ever told you how much you remind me of my uncle, Uriah Twin-Hammers?
Korgan: Watch yer step, gnome. If ye make me angry, I’ll bury the head of me axe so far up yer backside yer breath will smell like magic metal!
being quite rude to the lovely Aerie:
Korgan: Aerie! Aerie! Cease yer whining! I’d swear on me father’s coalcart ye were one of o’ them fey elves with all the blasted cryin’ coming from ye.
Aerie: Eek!
asking Cernd the druid for rain:
Korgan: Rain-maker, use yer mumbo-jumbo and make sure it don’t rain when we’re travelling in the outdoors! It makes me armor rust, me clothes damp and me feet slosh about in me favorite boots.
Cernd: I’m afraid not, Korgan. It is not within my sphere of influence, nor is it my place to do so.
Korgan: Bah! Tree-hugging dirteater! If yer god lived on Faerun I’d break his windows! Good fer nothin’! Go pluck mistletoe and frolic naked in the glades!
Korgan is hysterical.
Honestly? Grand Theft Auto III. For stupid reasons.
There’s a little guy that walks around near the police station, constantly spouting off random lyrics from The Village People’s “YMCA.” Cracks me right up.
And of course, there’s Minsc, the not-so-bright Ranger, whose best friend is the hamster Boo.
getting to know the lovely Aerie:
Minsc: Aerie! Boo has been mulling over a question for you. Never have I seen a hamster concentrate so! He has been so very quiet I thought perhaps I rolled over him last night, which caused me great concern.
Aerie: If ‘Boo’ wishes to ask me a question, Minsc, then he should feel free to do so.
Minsc: But Boo’s question is of such a personal nature … well, the thought of it makes me blush right down to my buttocks.
Aerie: I … see. Perhaps Boo should ask me anyway just to get it off his chest. We … wouldn’t want a hamster to bottle up all that anxiety, now, would we?
Minsc: You are very insightful! Such bottling could lead to all sorts of un-hamster-like explosions! Well … Boo wonders why you do not perform all of your duties, since you are our witch?
Aerie: My duties? I thought you were supposed to protect me … I didn’t know there were any duties involved. And what’s so personal about this?
Minsc: Well … a Rashemani witch accompanies a ranger on his dajemma and teaches him the lore of herbs, among other things. Well … Minsc and Boo have discovered a need of some of this lore, maybe. After frolicking in a bush that we now consider to be of a suspicious nature, both Boo and I have contracted the Calimshite Itch in rather … private places. A salve would be most joyously anticipated!
Aerie: I … I … I’ll do what I can, Minsc.
Minsc: Many thanks, Aerie! Maybe, soon, Boo can return his little mind to thought of butt-kicking instead of butt-itching, and I for one shall be very relieved!
chatting with Cernd the Druid:
Minsc: Cernd, you are akin to nature as I am. Why did you not take up the blade to fight? I do not think I would have the patience you do in battle.
Cernd: The great oak might crush a building when it falls, but the sapling that seeps its roots through the foundation will stop the building in the first, lest the cellars leak and the fungoids take the builders.
Minsc: Confused looks from all sides but Minsc understands!
The depth of that game is astounding. Worth many, many hours of play.
Not sure why I double-spaced that last one. It’s late.
From the Splinter Cell games.
…
American Soldier: You’ve come to save us! Where are the others?
Sam Fisher: It’s just me.
American Soldier: Aw, crap.
…
Fisher: Tell me what you know about your friends on the inside.
Terrorist: I don’t speak English.
Fisher: I’d bet your neck you do.
Terrorist: Well, maybe I speak a little English.
…
<Fisher sneaks up on a guard in Japan and grabs him>
Guard: Agh! I knew it! I kne there were ninjas around here!
Fisher: What?
Guard: Yeah, you gotta be a ninja. How else could you sneak up and grab me like that?
Fisher: Listen, I don’t know what…
Guard: Wow! A real, live ninja! I can’t believe it!
Fisher: Listen, I’m going to kill you if…
Guard: Wow! Killed by a ninja…cool!
…
Marc
I can’t pick just one!
“I like shorts. They’re comfy and easy to wear!” - Pokemon Red/Blue/Green/Yellow
A million from Full Throttle:
If you use the mouth icon on the piano, Ben says: “It’s hard enough to play with your fingers.”
Girl (forgot her name): “Nice forks! Where did you find them?”
Ben: “Right next to the knives and spoons.”
And of course Ben’s: “I, uh, fixed your door. <pause> It was sticking.”
**Sam and Max Hit the Road ** (can you tell I was a fan of the LucasArts games back in the day?):
Max: “I’m not a malefactor, I’m a lagomorph!”
Sam: “I wonder what causes these inanimate objects to dance their infernal jitterbug.”
Max: “I think it’s all controlled by really big magnets beneath the Earth’s crust.”
Sam: “You’re an ignorant dolt, Max.”
Sam: “Percent sign, ampersand, dollar sign.”
Max: “And colon, semicolon too!”
Psychic: “What are you doing?”
Sam: “Swearing in longhand, asterisk-mouth.”
And far, far too many from Earthbound:
“It’s ok to visit him here, but don’t wander around the building. Someone might be suspicious and take a pot shot at you with a machine gun.”
“Hey dudes! It’s summer! It’s the manly time of year! Time for sports, guys!”
“Since you left home on your journey, things have changed around here. For example, I don’t have as much laundry.”
“Spankety spankety spankety!”
“You Spoony Bard!”
“Barf!”