Get off my dick about not getting a vaccine yet (not anti-VAXX)

[LSLGuy]

@BigT

Due to my anxiety and trouble sleeping the night before, it was also a bit disorienting. But I got it done, and am ready to get the second shot–even if I am a bit anxious about the side effects.

Welcome to the club! Good on ya for beating anxiety.

We’ve got a QZ thread on the second shot. I’m on my phone or else I’d cite it.

Experience varies from nothing to a couple days felling ill but not being ill. Nothing to truly fear. The anxiety can be beaten as you’ve just proven to yourself.

[Thudlow_Boink]

@BigT

and was asked if this was my first or second shot.

Now that you say this, it occurs to me to wonder whether the two shots are identical.

[Folly]

For Pfizer and Moderna at least the two shots are the same, dosage amount and everything.

[Thudlow_Boink]

Thanks. Mild curiosity satisfied.

[BippityBoppityBoo]

@LSLGuy

Welcome to the club! Good on ya for beating anxiety.

@LSLGuy

Experience varies from nothing to a couple days felling ill but not being ill. Nothing to truly fear. The anxiety can be beaten as you’ve just proven to yourself.

Good post!

[LSLGuy]

Quoting myself for context:

@LSLGuy

We’ve got a QZ thread on the second shot. I’m on my phone or else I’d cite it.

@BigT - I’m back to my desktop. Try these:

Dreading the second dose

I just got off the phone with someone who received his second dose of Moderna’s vaccine 4 days ago. He describes a severe reaction that almost landed him in the ICU. His symptoms began 8 hours after his (second) shot, and included fever, chills, severe body pain, extreme somnolence, and fatigue. He was zonked out for 4 days in a row, and is now slowly getting his energy back. He is 78 yo and is diabetic but is very well controlled on insulin. This doctor explains it so well: the second dose of …

POLL: How was your vaccine reaction?

I’m on day 3 of feeling like heck from my first Moderna shot. I thought I’d throw out a poll to see how everyone is doing, now that there’s a steady stream of vax happening. Enjoy. poll poll Note that if you’re on a two shot regimen and you’ve only done one shot, you can answer the first poll now and come back later to answer the second one. You can change any vote after you’ve voted.

[BigT]

@LSLGuy

@BigT

Due to my anxiety and trouble sleeping the night before, it was also a bit disorienting. But I got it done, and am ready to get the second shot–even if I am a bit anxious about the side effects.

Welcome to the club! Good on ya for beating anxiety.

We’ve got a QZ thread on the second shot. I’m on my phone or else I’d cite it.

Experience varies from nothing to a couple days felling ill but not being ill. Nothing to truly fear. The anxiety can be beaten as you’ve just proven to yourself.

Honestly, the most anxiety I felt was right before the phone call to set up the appointment. But I just waited it out a bit until it subsided. The issue on the day was just that, for the first time, it felt hard to breathe a mask, suggesting I was hyperventilating a bit. Like I said, the experience was more disorienting. I expect it to be less so next time, now that I know what to expect.

[hajario]

Good for you for pushing through. I am trying to coax one of my sisters into getting a shot. She finally opened up to me some more today and I am pretty sure that it’s more anxiety than stubbornness. Once I realized that, I had a much easier time getting through.

[hajario]

We may have turned the corner on my last holdout sister. It was a combination of tough love from my stepmom (her mom) who said that she can’t come to her house if she’s unvaxxed, explaining the science from her nerdy brother (me) and loving patience from our other sister. I am really happy.

[LSLGuy]

Hooray! 1 down, 25 million 24,999,999 more to go.

[Tamerlane]

@hajario

It was a combination of tough love from my stepmom (her mom) who said that she can’t come to her house if she’s unvaxxed, explaining the science from her nerdy brother (me) and loving patience from our other sister. I am really happy.

Congratulations, that is honestly very encouraging . There was in article in the WaPo today about some vaccine-adverse people that have been converted through a variety of messages. Some progress is slowly being made.

But you head the man…

@LSLGuy

Hooray! 1 down, 25 million 24,999,999 more to go.

Get busy hajario !

[Esprise_Me]

This is really encouraging to hear; thanks for sharing!

[hajario]

@LSLGuy

Hooray! 1 down, 25 million 24,999,999 more to go.

Plus my brother in law and niece (who is 18 today). So actually 24,999,997!

[LSLGuy]

Wow! You’re on a roll! You should bottle that and sell it. Just don’t call it a vaccine against anti-vaxxing.

[Gatopescado]

Stupid Question: Couldn’t they alter the delivary system? Maybe a pill or patch, for those averse to All Things Needles?

[kenobi_65]

@Gatopescado

Couldn’t they alter the delivary system? Maybe a pill or patch, for those averse to All Things Needles?

My understanding is that these particular vaccines are designed to be administered into a muscle. I suspect that pills or patches won’t deliver it where it needs to go.

As per this NY Times article:

The Covid-19 vaccines are designed to be injected into muscle, and the muscles of the upper arm are convenient for shots and thought to be less painful than some other areas of the body. But a vaccine can be injected into other muscles, provided they are near some of the hundreds of lymph nodes that exist in the body. The upper thigh, for example, is located near multiple lymph nodes and has already been shown to generate an effective immune response after vaccination.

[Gatopescado]

Interesting. My upper thigh has no sensation at all. Been that way for years. Don’t know why.

Well, I got a clue. I ski, and the upper thigh is a HUGE part of what I do. Always has been. Maybe it just done wore out., tingley-wise.

[needscoffee]

@kenobi_65

My understanding is that these particular vaccines are designed to be administered into a muscle. I suspect that pills or patches won’t deliver it where it needs to go.

They’re being worked on. From here:

Your COVID vaccine booster might be a patch or a pill. Or it might come with...

Excerpt:

Skipping the needle

There’s also a substantial effort underway to come up with vaccines that don’t rely on needles and syringes to be administered, after record demand strained the complex global supply chain amid the pandemic. Some projects could make it easier to store and transport the vaccine, without the expensive freezers and dry ice currently required for the Moderna and Pfizer vaccines.

For example, future doses could be inhaled through the nose instead of shot into arms. The NIH recently touted promising results from a single-dose intranasal vaccine tested on monkeys, similar to AstraZeneca’s.

The Biomedical Advanced Research and Development Authority (BARDA) last year also announced millions of dollars in contracts to develop a handful of other alternatives delivered by wearable patches or pills, deploying the agency’s experts to shepherd developers through early trials and regulatory approvals.

Vaxess Technologies claims its self-applied patch is shelf stable and painless, delivering its vaccine through microscopic “projections” that dissolve into the skin.

“We’re working with the companies, with the different technologies, to potentially partner them with the six vaccine candidates that are currently being supported by the U.S. government,” said BARDA Director Gary Disbrow.

BARDA hopes the firms can show in smaller trials that they trigger the same kind of immune response as the currently authorized vaccine doses, which could speed their availability to the general public.

[puzzlegal]

I was going to cite a very similar article in today’s WJS.

https://www.wsj.com/articles/next-generation-of-covid-19-vaccines-could-be-pill-or-spray-11620034381?mod=series_covidvaccine

The next generation of Covid-19 vaccines in development could come as a pill or a nasal spray and be easier to store and transport than the current handful of shots that form the backbone of the world-wide vaccination effort.
…
There are 277 Covid-19 vaccines in development globally, of which 93 have entered human testing, according to the World Health Organization. Most of the vaccines in clinical testing are injected, but there are two oral formulations and seven nasal-spray formulations.
…
Another challenge that companies developing next-generation Covid-19 vaccines may face: finding enough people willing to receive unproven vaccines or placebos in clinical trials at a time when they can also get one of the authorized shots that has already been proven effective. An Altimmune spokeswoman said it is getting more challenging to find subjects, but the nasal-spray formulation has enough appeal to continue to draw volunteers.
…

[hajario]

@hajario

Plus my brother in law and niece (who is 18 today). So actually 24,999,997!

I just got off the phone with my sister. She and her husband are getting the J&J in an hour. We just got off the phone.

My niece turned 18 yesterday. She has wanted the Pfizer for months but her mom wouldn’t let her. The first thing that she did on the morning of her birthday was go to CVS and get a Pfizer jab. I am so proud of her.