My band played at a club in denton called the library. Perfect for a college town. When the parents call"oh, hes at the library"
In the game Max Payne, there is a night club called “Ragna Rock”
There’s a bar in the Chelsea section of Manhattan called Ear. The reason for this is that the place used to have a big, red neon sign out front that read BAR in block letters. Part of the sign burned out, making the B look like an E. The owners never got around to fixing it, so eventually everyone started calling it Ear. And they still do.
When I passed through Denison, Iowa, I saw a bar called Book 'em, Dan-o. I didn’t go in, but I kind of wish I had.
Real:
Beaver Liquors in Colorado
Fake but should be real:
Master Bait & Tackle
I drove by a restaurant in up-state Pennsylvania, named “Little Greek Boys” Hmmm…
Here in Houston there’s a fairly old (by Houston standards)sushi restaraunt in a ritzy area named “Back Door Sushi”.
Eeewwww.
The Funking Conservatory: it’s actually the last name of the people who run it, a school for professional wrestlers. Got to be real careful saying this.
The Get Lucky Guesthouse: a guesthouse in Amsterdam. I stayed there based on the name, but I’d suggest it to anyone - nice people run it. Of course it’s near the District.
A good friend of mine used to have his own drywall business:
Well Hung Drywall
He got lots of business from people who just wanted the t-shirt.
I dream some day of opening a combination of pet-store and Natural Foods:
Herbal Gerbils
Eh? eh?
::crickets::
Oh well, it was worth a try…
This isn’t exactly in the same vein as the other responses, but it certainly caught my eye. In a small town in New Hampshire, near Hanover, is an establishment called ‘The Unamerican Activities Investigation Committee.’ Sadly, I wasn’t able to visit 
<hijack>
Any NH Dopers who know the actual purpose of the UAIC? I did a Google search with no results.
</hijack>
There is a restaurant in Vietnam named “My Dung”
Mmmm…yummy
There is an “Amigon” funeral home I saw in the midwest.
Am I gone?
I saw a gas station/restaurant sign that boasted “Kids with gas eat free.”
what a deal!
I saw a doctor’s office with a large sign in Logan, WV:
Dr. Pimpa, gynecology
“Babies on Amsterdam”? Huh? Me lack clue. No get “mildly funny”. Help clue lack man grok ha ha.
I go there often. Best damn chinese food around!
If I had a buisness I’d name is Uranus Hertz.
~Kittie
It’s amazing how much more lucid one is when they’re on here first thing in the morning.
Two other REAL candidates from the pissant white-bread mountain town I call home include:
The Vietnamese restaurant called ‘A Dong’.
The chinese restaurant and karaoke bar called ‘U Sing’.
Why is it that asian cuisine and dubious nonmenclatures go so well together?
For a while in Arlington, Texas there was a sign visible from Highway 183 for Murphy’s Law Legal Services.
Ahem. That would be Irving, not Arlington, for the DFW-savvy. Near the MacArthur exit, I believe.
Bar in a college town: The Library.
There’s an old building several miles south of the town I live in which looks like it came from a main street of a small town about 130 years ago, but sits all by itself on a dirt road out in the middle of nowhere. In front is a bunch of rusty old road construction equipment. The sign over the door says “Expanding Contracting.”
In Osaka, there is a chain of bars called ‘Someplace Else’ (I used to frequent the one at Triangle Park in Amerika mura).
As in, “Where have you guys been?” “Someplace Else.”
In Kobe, there is a really nice restaurant, overlooking Kobe Bay near the ferris wheel, called Mosaic (great paella). Trouble is, “mosaic” in Japan means the square fuzzy big pixels in front of genitalia in pornography. Lots of people eat there, anyway.
In Hong Kong, buying milk from “Kowloon Dairy Company” makes me wonder if the milk contains mad cow disease.
Phil: You mean Clifton’s Web, right? That’s where I got my Abbie Hoffman shirt. I used to live in Lakewood. Man, that was the life.
There’s a business I drive past that’s called “Patriot Supply”. I keep thinking it **should]/b] be a gunshop or a surplus store.
But no, its just a lumberyard. This is new england after all.
Wow, my family has talked about how cool it would be to start a restaurant called Someplace Else.
My roommate has a pair of boxers with the phrase “I got my crabs at Dirty Dick’s.” Dirty Dick’s, being, of course, a seafood restaurant/store (not sure which, I forgot to ask her).
There’s a Vietnamese foodcart and restaurant in Madison called I’m Here.