As others said, in American Football, not a chance. There’s a lot of rules in place that would make it impossible for the swam effect to work. For one, you cannot use other players to prop yourself up, so there’s nothing to stop the defensive linemen from just diving over. So any offensive plays by the kids starting under center are doomed. The shot gun might work, but even if you allow rule changes to have more kids on the line and/or more receivers, their QB will be heavily blinded by the much taller defensemen, he’ll have to throw with a lot of arc, and he’ll still have limited time to make reads. As a result, the passes will mostly be up for grabs and not be deep, since the QB has maybe 1.5-2s to throw, so I see them being easily defended or intercepted. Run plays are doomed simply because as many kids as it would take to block the linemen would make running inside impossibly cluttered, and running outside would leave linebackers and safeties free to fly to the ball if they could even get outside, which is unlikely.
On offense, it’s the exact opposite. Defensive pass interference would leave it impossible for the kids to stop the QB from just lobbing it up and allowing the receiver to easily outreach his defenders for the ball. Running would easily gain a minimum of 4-5 yards. They can’t make contact with the offensive linemen before the play, so the kids would be unable to match the surge. And, of course, the running back would have no problem leaping well over the line since no one would be able to match him. Frankly, chances are you’re looking at a bad offensive play being around 10-15 yards, with most of them resulting in touchdowns.
It would be a massacre, even with more than a 9.9:1 ratio.