Super-powerful villains who can be defeated (or greatly hindered) by the lowest of heroes

Charlie Collins vs. the Joker*.

Charlie is a regular working schlub, a “nobody”, who ran afoul of the Joker in the Batman Animated Series episode “Joker’s Favor”. He gets terrorized, browbeaten, stalked, and nearly murdered…and then, the Joker threatens his family. Soon after, the Joker is clinging to Batman, begging to be saved from Charlie, because Charlie has figured out exactly how to terrify the Joker. In a final twist of the knife, he gets a laugh out of Batman before casually driving off to have dinner with his family.

*Okay, the Joker isn’t “super-powerful” in the sense of actually having superpowers, but he is portrayed as incredibly dangerous and resourceful compared to ordinary people.

Charlie Collins vs. the Joker

The Golem

This clip chows how underrated a whip can be.

The various Scourges (NOT Skurge) vs. almost anyone. They killed at least half of Marvel’s rogues’ gallery in the 80s. And they weren’t really superpowered…just well-trained in hand-to-hand, marksmanship and disguise.

The story where Ka-Zar defeated Thanos was a bit of an embarrassment.

No, that was when super-evil computer Computo destroyed her third body when she was split up. In the next panel, she is smiling about her other two bodies being saved!

Well, that’s not even Only Mostly Dead.

Good lord, a Dalek?

They have similar propulsion systems! Staircase Boy could defeat the Computos.
And thinking about that just made me realize…the Legion can’t attack cause Computo is holding Legionairres hostage…but they’re just rolling computer banks with bubble heads who are going to take over the Earth. The Science Police should have been all about blasting them from space. Screw the handful of hostages, these guys are going to take over the Earth!

Dazzler tended to think she was pretty underpowered until The Claw grabbed her and she kind of ate him by accident. He got better, though.

Superman can be defeated by a rock. A ROCK!

I, carrying said rock, can beat Superman.

Therefore… me vs Superman is the obvious answer to this thread. :wink:

One of the best lines from The Big Bang Theory:

Raj: I like Green Lantern, I’m just saying it’s pretty lame that he can be defeated by the color yellow.
Sheldon: Only the modern Green Lantern is vulnerable to yellow.
Leonard: Golden Age Green Lantern was vulnerable to wood.
Raj: Great. So I can take them both out with a number 2 pencil?