That cracks me the hell up every time.
People who have no clue what the Airplane! movie is about, who never saw it or heard of it, crack up when I say “And don’t call me Shirley.”
I saw an interview with Leslie Nielsen, who stated that people use to come up to him on the street, say “And don’t call me Shirley” and then walk away. He had no clue that sentence would become a meme.
Oh! You have a guitar! 
Surely it’s been more than 30 years since the movie came out?
It has, and don’t… well, you know.
FWIW, I laughed the hardest and longest at this scene. Not funny, my sweet white ass!
In the article, it mentions that none of the reviewers knew who the hell Barbara Billingsly even was. Hence they could NOT appreciate the truly outrageous humor in the bit, seeing Mrs. Cleaver talk like that.
As a medical professional and hence official compassionate person, the sight of having a kid’s IV ripped out like that had me rolling on the floor with laughter. And it still amuses . . .
All humor is based in pain, after all.
I asked my daughter (22) about this after she saw the movie for the first time not too long ago. To her, Barbara was just “an old lady who spoke Jive,” which made it funny. Of course, I explained the whole “Mrs Cleaver” thing to her.
Now that I think about it, no one under the age of around 50 is going to make the connection between Leslie Nielsen, Lloyd Bridges, Peter Graves, and Robert Stack and the iconic roles they played (John Bracken, Mike Nelson, Jim Phelps, Eliot Ness). They probably have no idea who Ethel Merman was, either. 
Or even know about Airplane!. Several years ago I watched Scary Movie 3 (I think it was 3) in the theater, and I was clearly the oldest person in the audience. There’s a scene toward the end of that movie where the two main characters, a man and a woman, are attempting to defuse a big bomb. They’re sweating over the task when Leslie Nielsen sticks his head in the door and delivers his “… we’re all counting on you” line.
I was literally the only person in the audience to laugh at that. Many heads turned my way, faces wearing that “what was so funny?” expression. I realized that nobody in the audience was old enough to remember Airplane!.
The same thing happened to me the first time I saw Blazing Saddles (December ‘73 or January ‘74) and they got to the scene with "Badges? We don’ need no steenkin’ badges!"*
*The line was originally from the Humphrey Bogart movie The Treasure of the Sierra Madre (1948).
My absolute favorite joke/exchange was actually #1 on that list!
Also, thanks for that list! It was hella entertaining.
Give credit where it’s due; Jill Whelan totally makes that scene work.
Are you counting on it?
Say no more, say no more! 
I was just looking at Joke #3 on the complete list. Isn’t the way Joey is staring at that model plane very … suggestive? :dubious:
Commiserations, old man. I was the only person in the theater watching “Twilight Zone: The Movie” who laughed at the line: “I told you guys we shouldn’t have shot Lt. Neidermeyer!”
Hell, the interval between those two movies was only about four years, IIRC.
“I want the kids in bed before ten, the dog brought in, the cat put out, and tell the milkman: NO MORE CHEESE!” 
One seems to be missing (or rather, #60 is incomplete), but that’s okay because I didn’t get that it was a joke myself until years later.
Controller: [talking on telephone] But this Striker guy has no airline experience at all, he’s a menace to himself and everything else in the air. [pause] Yes, birds, too.
[camera pans left]
McCroskey: Okay, I know! But what other choice have we got? [hangs up phone]
It was a long time before I realized they were supposed to be talking to each other, via telephone, across a distance of about six feet.