I was in Boy Scouts with a guy who now has four Grammys and two Emmys.
Opioids. They don’t work on me very well. Novocaine might or might not.
After my hysterectomy I got a prescition for hydrocodone with tylenol. I took two pills, got little relief and piteously begged dad to get me some OTC ibuprofen. Worked so much better.
It’s a miserable thing to have inherited from mom.
Have you been genetically tested?
Hydrocodone is metabolized to hydromorphone (synthetic morphine) by the CYP2D6 liver enzyme. 25-30 percent of the population possesses mutated CYP2D6 genes that produce little or no CYP2D6 enzyme. If hydrocodone isn’t metabolized by CYP2D6, there is no pain relief. Well, it is also metabolized by CYP3A4 to norhydrocodone, but that is a much less effective pain reliever. And some people can be CYP3A4 poor metabolizers also.
For the record, the only reason I know this is because I’m also a CYP2D6 poor metabolizer.
Which I just realized was 35 years ago yesterday (the day before).
I had no idea until right now you could be genetically tested.
My family tree can be traced back into myth.
Not sure how to reconcile that, but there doesn’t seem to be anyone seriously challenging it, out of respect for a culture I guess.
Also just remembered… i’ve played at Ronnie Scott’s !
ok, upstairs, not the main jazz club.
Ok, I’ll bite. World championships of what?
Nothing anyone is likely to have heard of, an obscure class in a relatively niche sport. So, cool to me, but not so cool in practice 
That was rather the idea of the thread, though I didn’t make it very clear!
My name is on a plaque in the bell tower of the Old North Church in Boston, the one in which the signal lamps were placed for Paul Revere’s ride. I was one of the bell ringers for the first peal rung on the bells. (Anyone familiar with change ringing will know what that means, it would be a long explanation.) Paul Revere was familiar with the tower because he was one of the bell ringers for the church in his time.
I live in a city of about 24,000 people in 4.2 square miles. About five years ago, I spent a year running every street in the city.
I’ve briefly piloted a blimp.
That’s about it, really.
My city (town) is roughly the same size, with about 20K of population. Ten years ago, my college history prof and his wife walked every street in the city. They were both in their upper 70s and I think it took them about 18 months.
I’m pretty sure that neither of them ever piloted a blimp, however.
You guys are all pretty interesting!
The interesting thing about me is that I’ve won an election - twice!
I try to remind myself of that when I do something really stupid. Like “hey man, chill out. People voted for you.”
- I’ve met 4 different POTUS’s.
- I worked as a zoo keeper for a group of 4 different North American black bears for a period of two years.
- I have met and advised 8 different billionaires during my career.
- I have been deposed in 4 different legal proceedings, once by the FBI and testified for the prosecution in a criminal case against a former client, who was convicted based upon my testimony.
- I was recruited by the FBI, early in my career, but I turned it down.
- I have flown on probably close to 20 different private jets in my lifetime, multiple times.
- I have had two different brushes with death that I am damn lucky to have survived.
One thing I want to do, but haven’t had the opportunity, is to drive a zamboni.
Did you advise them to give you lots of money? I certainly would’ve entertained the idea on occasion.
If you had, you would have won the thread, hands-down.
Dang, way to leave us all in suspense.
My right foot is one FULL shoe size larger than the left.
I worked for a couple months on a Soviet fishing boat just before the collapse of the Soviet Union. The ship was called the Sulak. This boat was used as a model for the titular ship in the book Polar Star by Martin Cruz Smith.
I just discovered I am clearly visible in Street View on Google Maps. I saw the Google Maps car drive by three weeks ago, and today they posted new pictures for that location.