Wire in the Blood

What does this BBC title mean?

I know nothing about the show, but “The trilling wire in the blood” is a quote from part II of T.S. Eliot’s Burnt Norton from Four Quartets.

Having read most of the books in the series (all of which take their names from T.S. Eliot) and having just finished watching the series through the end of season 3 (Netflix)…I have no idea what it means.