Wow, 80 posts and no mention yet of Judd Nelson?
Mike Myers as “Austin Powers”.
Costner, though I liked “Dances with Wolves” and “Robin Hood” despite his being in them.
My reaction to Tom Hanks depends on the movie. I really hated “Castaway”, but liked him in all the roles he’s done as a comic actor–especially in “The Burbs” and “Big”. As a “serious actor”, he was very good in “Road To Perdition”. In a lot of other dramatic roles, any of 10-12 other actors could have read the lines as well and for less money.
Among dead guys, I never liked Richard Burton.
I liked Richard Gere in “Chicago”. Don’t care for him otherwise.
I hated “Titanic”, but otherwise have liked DiCaprio in everything else I’ve seen him in.
Jim Carrey - the gurning-faced twat!
The second one on my list (after Cruise) is Nathan Lane. Something about him irks the hell out of me.
Tom Cruise.
After he made all that noise about that South Park episode on Scientology, he comes out looking like a douchebag.
Dom DeLuise, Tom Cruise, Ben Affleck, Jason Lee, Madonna, and Sarah Silverman. Especially Sarah Silverman. Oooh, and Alec Baldwin, except for when he’s hosting Saturday Night Live, which is, oddly enough, the only time I ever watch Saturday Night Live (and it has nothing to do with his politics, something about him just bugs me, except for when he’s hosting Saturday Night Live).
David Caruso - I don’t know where to start and if I did, I don’t know if I could end.
Will Farrell - He’s funny? Really?
Christian Bale - Has one expression. Close your mouth already. I mean, come on, you already have one bat cave.
Josh Hartnett - You are a chameleon.
Adam Sandler doing anything but the waterboy.
Anything with Jack Black- he ruins everything he is in with his “wild guy” schtick.
Whoever told him his little crazy guy bits are funny lied to him. Not funny, ever.
Not even once on accident. Not even his little rock group- lyrics that would embarass a third grader. And the fact that even in interviews he has to be “on” makes it worse.
Two pages and no mention of Andy Dick?
Since I know none of these people (nor do they know me) I’m going to be brutally honest about them:
Nicole Kidman: Nothing quite says “I keep a knife under the bed & and I’m just waiting for the chance to castrate you as you sleep” quite like Nicole’s face. In every role she has ever played. In “Cold Mountain”, she literally made me root for the North (but I knew even desperate wounded and starving civil war soldiers who hadn’t seen a woman in months wouldn’t have her).
Ben Stiller: Honest To God, WHO keeps casting this creep!? I’m sorry that your family told you your whole life that you had talent. Hint: They were Lying.
Luke/Owen Wilson: See Above.
Nicholas Cage: I suppose ugly hairy men with arms longer than orangutans should be given a chance to act, if they have talent. Sadly, Nick, you’ve closed the door for all of them. If there’s a Hell, being forced to wax Mr. Cage’s back for all eternity is definitely one of the lower levels.
Kyra Sedgwick: Another ‘why does she get cast when she has no talent?’ PS- the only way that face marries Kevin Bacon is sitting in a manilla envelope in a safety deposit box somewhere.
Will Farrell: Dinner-theatre is calling; please don’t be late.
Ashton Kutcher: Here’s a dime. Call your mother. Tell her you still can’t act. What, you need a quarter? Guess you’re ‘punked’. yawn
Cybill Shepherd: Why, of Course all Models make great actresses. Just ask Cindy Crawford. Its been more than 15 minutes…tick-tock, tick-tock…
Holly Hunter: Nope. Not getting it. You have the sexual-chemistry of sleet and freezing rain. Try plays.
Mariska Hargitay: Take off the Klingon outfit, you’re on ‘Law & Order’. What do you mean, the ‘cranial ridge’ isn’t a costume…?
Reese Witherspoon: I hear its hard for Talented Child Actors to get work as an adult. Probably because Hollywood casts losers like you instead. There’s a place for you to learn your craft; its still called ‘away’. Go back there. Now.
Brittany Murphy: Don’t you think girls named ‘Brittany’ have it hard enough in life w/o being blamed for your crap acting?
Jessica Biel: “Worst Impression of a Walton” award, 2006. “…'Night, Jessica.”
Kate Hudson: With a face that flat, you’re supposed to have a great personality or talent. Sadly, you don’t even have a good ‘chasing parked cars’ joke in there. PS- Can’t the vet fix those Shizhu eye-teeth?
Yet, without even mentioning a movie in your post, I knew who you were talking about. Those guys get that a lot, I imagine.
My list:
Julia Roberts (big mouth, annoying laugh, homely)
Robin Williams (like someone upthread mentioned, he’s the same character in every movie)
**Meg Ryan ** (post When Harry Met Sally)
the aformentioned Wayanses
**Jennifer Aniston ** (I don’t know what anyone saw in her performance in The Good Girl. It was a good movie, but her performance was stiff and unbelievable)
**Tom Cruise ** (I can’t look past the batshit craziness)
Hey, you just described my whole day’s schedule.
Sorry, but she’s hot. The film may suck, but that’s not why you go to see such a film.
I’m not bursting with originality today…could you say something nasty about Bruce Willis for me? 
Bruce Willis. Arrogant w/o basis. Living proof that Rogaine (and possibly steroids)makes you angry. To this day, the reason I think ‘Moonlighting’ worked was because there were two miserable arrogant leads who the writers truly enjoyed taking down a peg and abusing on a weekly basis.
Made a career/image out of pissing contests. Married Demi Moore and started her pregnancy assembly line. Is supposedly very devoted to his kids (but still supposedly banged the starlight out of Lindsey Lohan less than a year ago, who is younger than his oldest daughter, so don’t think ‘Father of the Year’. And Please Og, don’t let us get stuck watching Lohan for as long as we’ve been stuck watching DemEEE.) Sadly, he won’t go away. Expect him to do more & worse crap films in future as somebody still has a s-load of child support to pay…
I use to avoid Julia Roberts until she betrayed me by starring in My Best Friend’s Wedding, a movie that was actually good. Now I have to actually watch her movies before I judge them. What a bitch.
Ahhhh, thank you! That’s good stuff. 
I find myself nodding through this thread.
Here’s my list:
Tom Cruise–hey, Risky Business was fun, and Rainman was moving, and Jerry MacGuire was neat, and now you need to STFU and get some therapy.
Jim Carrey-I would loathe all he’s done, except for Eternal Sunshine. His voice grates on my nerves and his rubbernecking is old and lame.
Leonardo–pretty boy, go model for Abercrombie. And shave off that ridiculous goatee thingy on your face. Ugh.
Bruce Willis-I can blow people up real good, I just can’t act.
Adam Sandler-why is this man on the screen? Surely there are cars that need to be valet parked.
Keanu Reeves-what does he do, except grow shiny hair?
Will Farrell–I second the dinner theater call–and let’s make it in the round.
There are more, I’m sure-I just can’t think of them at present.
Women:
Nicole Kidman-a dash of cold water on everyone. She can ruin a comedy quicker than the PC police. She’s not funny, not witty, not fun. And stop changing your hair, already!
Meg Ryan-I used to like her, until I realized that she plays the same person in every film she’s in. I got tired of her persona in Kate and Leopold --a very stupid movie made more stupid by Meg’s hair. Yes, her hair.
Julia Roberts-I happened to catch Oprah one day just after the Oscars. Julia was on (she may well have won- I don’t remember). She is just such a brat-some guest complimented another guest on her dress and Julia piped in with-“I notice you don’t say anything about my dress.” or words to that effect. Yep-it’s all about YOU, babe. Moron.
Lindsay Lohan–you were so cute in Parent Trap --and now you are Bad Example to all teen females. Thanks for that, skank.
Drew Barrymore–someone needs to tell her that the cute, sassy kidlet thing is old, old, old for her-she’s not in ET anymore.
Renee Zellwegger–can you scrunch your face another way? Just for a change, you know? Please?
This is fun!
In fairness to Mr. Williams, he’s not actually the same character in every movie. He has two characters. There’s the comic character (Mork, the Genie, the guy in Good Morning Vietnam, etc.) and the serious character (Good Will Hunting, Dead Poets Society, What Dreams may Come, etc.).
Tea Leoni. I doubt she’d change her expression if you smacked her in the face with a tubafor. She couldn’t portray “falling” if you pushed her off a cliff.
Drew Barrymore. Always with the smirk. Someone needs to slap that smirk off her. Anyone dumb enough to marry Tom Green has lost my respect forever.
Tom Green. I don’t think you can really call him an “actor”, since all he’s ever played is a jackass, which doesn’t require any acting on his part. At least on Jackass, they’re only hurting each other; Tom Green acts like an ass toward innocent bystanders, which is just plain irritating.