I have been wracking my brain for a way to approach women that doesn’t seem completely contrived. This has proven a difficult task since any attempt to engage a woman in conversation is indeed completely contrived.
I am assuming that most women understand this and respond to the most unique/least offensive pick up lines.
Two questions…
Is my assumption generally correct?
What is the best pick-up line you were ever approached with?
To my shame, I was once propositioned with “Excuse me, but would you mind if I got off with you?”
It’s important for women to know their friends like you and vice versa. Use this as your icebreaker. Something along the lines of “Your friend Meg is awful cute, you two ever kissed?” will work. When she is pleasantly surprised at how much you care for her friend, suggest a threesome.
Family is also important to most women. Statements like, “but your sister did this on the first date,” or “I see you have your mother’s breasts,” are real crowd pleasers.
Waverly is, in all likelihood, a single person. 
I like “Hi. My name is ___. How are you?”
Are you a ticket? 'Cause you’ve got fine written all over you.
“I’m a horny Martian. Take me to your beaver.”
In a college class I used the line “Would you like to study together sometime?” I followed this classic up by actually just studying with her. This may not produce a result you are ready for. It got me married.
I got propositioned with, “Kiss me if I’m wrong, but isn’t your name ‘Dominique’?”
If I said you were beautiful…
would you take off your clothes and do me right now?
Although, just to prove there are no absolutes when it comes to male/female relations: I did get pretty far (all the way, actually) with one girl who I made eye contact across the bar as I spoke the phrase “break my heart.” But the ironic thing was that I was having a conversation with my friend (about my ex-girlfriend), and used the phrase legitimately. But the girl read my lips and thought I was talking to her and came over and chatted me up… and as it turned out, it was just what I needed to get over my ex-g/f, who I had caught in bed with the biggest jerk I knew. (Grr… still annoys me. He really was number one on my asshole list.)
Oh, well maybe once. I had one girlfriend, a co-worker, come on to me by first grilling me with questions about things I’d discussed with a customer at a design review we had both attended (and where she had caught me looking at her legs), and then calling me right before lunch, chatting me up, and then saying “So why haven’t you asked me out for lunch yet? It’s almost 12.” I guess that was a pickup line.
I usually tell them, “I’m with the band.” Then, after that fails completely, I’ll try, “If I said you had a beautiful body, would you hold it against me?” Usually the bouncer steps in at that point.
So I go to bar #2. Actually, when I see someone I’m interested in, I just try to be myself. If that’s not good enough, then I start lying 
How you dooin?
Seems to me if you don’t want to appear as Mr. Teleprompter, you’d spend no time at all wracking your brain. The ladies will respond to honesty and spontaneity more readily than any line, so just concentrate on not being an inconsiderate jerk and you should do just fine.
Hello, my name’s Matt. May I buy you a drink? or Would you like to dance? or Would you like to step outside for some fresh air?
If you’re just looking to start a conversation, go for the laugh. If a guy can make me laugh with the first line out of his mouth I feel the need to see if he’s always that funny.
I wish I could give you a good example but I’ve had a long day & the only line that I can think of right now is the last one I heard.
“Can I buy you a drink or should I just give you the cash?”
Lines??? Where s’pose to use lines?!?!?! ACK!!! runs away
God, bughunter, I have to add that one to my sig:
Laughed my ass off…
Successful lines I’ve used:
Hey, want another beer? (never saw again after that night)
Hi, it’s too loud to talk here, want to go get coffee at the Roxy? (dated 6 months)
Npthing, just grabbed and kissed (Been with over two years and plan on marrying) (Okay, so I’d known her for 7 years)
How bout:
“Are you wearing intergalatic underwear, because your ass is out of this world.”
Not that this would work, but its pretty funny.
I’m pretty sure I mentioned this in another thread, but the most memorable line used on me was “Can I befriend you?”
Well, I was 19 and he was cute. It was a Kodak[sup]TM[/sup] moment…