If you’re an evil overlord, and you have an opportunity to kill your adversary simply and directly, say by shooting him at point-blank range while he’s defenseless, do it. Resist the urge to capture him unharmed and execute him more glamourously.
ALWAYS lift off and nuke the entire sight from orbit, it’s the only way to be sure.
If a ship with a new form of space travel disappears for eight years then mysteriously appears in a decaying orbit around Neptune, don’t go onto the ship to discover what happened to the crew, just blow it up and head home.
If you find a frozen alien in the antartic, do not unthaw it, do not study it. Destroy the alien, blow up it’s ship and go back to play the computer in a game of chess (which is a cheating bitch).
If someone offers you the adventure of a lifetime, say “FUCK NO!” and go back to bed where it’s safe.
If anyone says “it’s awful quiet around here” or anything that means the same thing, get the hell out immediately. Do not pass go, do not collect $200.
And if you’re not the Evil Overlord, but are on his payroll, leave as soon as you can. If you are his “Second in Command”, or “Right-Hand Man”, there’s probably no hope for you: you’re a gonner as soon as something goes wrong. But if you’re a mere peon, you might be able to request a transfer before the hero shows up and the Evil Overlord sends all his minions into the meatgrinder.