What can I say, I drank too much tequila last night. I’ve always wondered if there is a “best” way to get rid of this nausea and generally crappy feeling. I guess I’m looking for proven methods or home remedies. 
Unfortunately there is only one sure cure: time. There are many home remedies that entail all manner of vile concoctions, but the best thing to do is just have “a little hair of the dog that bit you.” Caution: this is only a good idea if you plan to stay at home and not go out again tonight! Note that the directive is " a LITTLE hair of the dog." You may not feel any better, but you won’t care! Some folks have some degree of success using vitamin B complex, but it varies from folk to folk. A big Bloody Mary made with V8 Picante and a pickled green bean and a giant green olive stuffed with onion, applied several times, seems to work for me.
Try drinking some Gatorade or other “sports drink” - a lot of your hangover headache is due to dehydration.
Kilt-wearin’ man (Johnson) is right!
Drink fluids, take some ibuprofen for temporary pain relief (no Tylenol or acetaminophen) and go back to sleep. I’ve also found that once you are starting to feel better, some moderate exercise will help.
Oh and do a SDMB search for hangover AND relief. There’ve been a lot of threads about this before.
Applejuice mixed with water, best way however is to switch to irish whiskey 
Aspirin washed down with a small drink of Andrews Liver Salts (bicarbonate of soda), then an hour of sleep.
Cecil Adams on hangovers.
Fried toad livers and haggis will make your hangover seem irrelevant.
So will lopping off my own head. But if it came down to deciding between self-decapitization, a hangover, or eating haggis, I’d have sit down and think about it. 
The best and only thing for a hangover–besides the hair of the dog–is to go out and jog for at least an hour (be sure you have re-hydrated from the night before). An hour and a half is even better. The endorphins will help physically, and psychological effects of excess alcohol consumption will be markedly improved.