I have been waiting to use “Jesus Christ on a tricycle” (from a fellow-doper) but the opportunity hasn’t arisen (snort, chuckle) in everyday life…
I find myself mumbling “dumb fuck” under my breath to bad drivers (I have children, must be careful, ever since my oldest said the c u next tuesday word…) and I tend to say “shit” for things that annoy me, like when I drop something.
But I am learning so many wonderful words to pepper my everyday conversation, right here on the SDMB…fuck nugget makes me giggle!
Margo
for some reason, lately it’s been;
Crap on a Stick!
See you in Toledo.
Rat bites.
Dimwad.
Sweet Mercy Magruder!
Mother of Pearl!
Futher of Muck.
My college girlfriends and I became quite fond of this odd gem:
Jesus-Criminy-Christ-in-a-bottle
You have to run it all together in a rushed mouthful.
When the situation really warranted extra emphasis, you could add “with chickens” at the end.
Another home-grown favorite that is the very flexible “shma”.
(you pronounce the “a” as in apple, as opposed to arm)
My friend, Carla, had a lovebird. Carla’s lovebird was a very cranky individual. When he was feeling particularly cranky, he was waddle back and forth on his perch and mutter (or the avian equivalent) “shma-shma-shma”.
Carla started incorporating it into her daily life. It started popping up in the event of a spilled glass of water or forgetting one’s keys. Soon all of our close friends were using it for all sorts of reasons. I have many memories of Carla hanging her head out the car window and yelling “SHMAAAAAAAA!!!” at drivers who cut her off or drove like idiots.
I apologize in advance, but seeing as how there already a lot of swearing in this thread… 
My standard outburst at stubbing a toe, or a really hard part of a video game that keeps beating me, or anything of the frustrating, I’m mad as hell I can’t take this anymore nature is:
Motherfuckinsonofacocksuckinmotherfuckinbitch. Said all as one word, with the emphasis on the first and last “fuck.” There are also random variations of this theme. There was no thought that went into composing this outburst, it just, well, happens.
Fuck nugget is also a good one 
Jesus Fuckin’ Diddly Dog Dammit Christ!
that’s mine. all mine.
Mine aren’t all that creative…son-of-a-bitch or fuck…
The curse I use most often is “Jesus fuck-a-monkey.” I’ve also been known to exclaim “Jesus!” but to pronounce it “hay-SOOS!” Lately I’ve taken to referring to people who annoy me as “jacknuts.” I don’t know what it means, but it sure sounds good.
Godzillatemple and I evidentally have read the same comics. I find Capt. Haddock’s curses too tongue-twisting, though, and I stick with “Aw, crumbs” if I’m in a Tintin kind of mood.
My favorite euphemism: “Cheese and crackers!” (“Cheese and crackers got all muddy!” in a particularly stressful but still mixed company situation.)
In the car, at other drivers: “Jackass!” is nice and satisfying.
Trusty all-purpose swear: “Aw, FUCK.”
fuckhead
my favorite term while driving
I’m partial to “assclown”…I don’t know why, I just am.
After visiting these boards I now use Asshat a bit.
There is one curse that I almost never use, but on those once in every five years or so times I get reaaly pissed at someone I say:
You cunt sucking mother fucking piece of shit!
It just seems to naturally role off the tongue. You don’t slur it, but ennunciate every syllable. Used it twice so far.
I’ve always been fond of W.C. Fields’ lines, like “Godfrey Daniel! Mother of pearl!”
Myself, I have heard myself muttering “Christus Maximus”, not so much in manner of cursing, but more in the spirit of general awe or disbelief.
– CH
Well, slap the dawg and spit in the fahr!
I tend to be particular to, in no particular order…
Fucktard
Fuckwicket
Asshat (thanks SDMB)
Cum guzzling gutter whore (this being used as an affectionate term for one of my close female friends, which usually results in us bickering back and forth using various curses, all in good nature)
Cockface
Penis Wrinkle
FotherMucker
Oh, and I can’t forget…
[strong bad]
Aww, HOLY CRAP!!!
[/strong bad]
I have recently started using ‘Monumental cunt-assed cock-fucker’, but it changes monthly, and usually stays about as meaningless.
Mark my words, you amalgamation of loathsome repulsiveness, for you will have your genitals sniggered at by witless eunuchs.
I use “utterly” for the F-work, “stupid” for the s-word, and “bucket” for both b-words. If you say them just right, people instantly know your intent: YOU UTTERLY STUPID BUCKET!"
They have all become very popular in my office, especially “bucket.”
I’m not an expletive guy, so my favorite curse would have to be…
“May someone backwash in your soda!”
Always seems to defuse the situation, too. 