Samantha Stewart in Foyle’s War, play by the improbably named but undeniably beautiful Honeysuckle Weeks. Feisty, smart, and able to put a suspect down in a pinch.
Lenina Huxley from Demolition Man.
Julie Newmar in the 60’s Batman series. Rrrowr!
Oh God yes… She was the instigator of one of my very few slack-jawed drooling episodes, with the other big one I remember being Salma Hayek’s “Satanica Pandemonio” dance with the snake in “From Dusk 'Till Dawn”.
I thought of her, but the big issue with that for me was that I wasn’t really invested in the character. Salma’s hot no matter what she does. 
My current one is Tulip (Ruth Negga) from Preacher. Man, there’s some je ne sais quoi.
Yvonne Craig’s Bat Girl too, double rrowr!
Absolutely this. Safety lights are for dudes.
Do yourself a favor: see the episodes Sasha Alexander did of Shameless (Showtime). That’ll give you some rigor mortis. 
It’s on Netflix; I’m there! Much obliged! 
C.J. Craig
and Hit-Girl.
Alyson Hannigan as Michelle in American Pie. Hot nerds turn me on!
(Hell, Alyson Hannigan in anything. She looks a lot like an old girlfriend of mine! :o )
If you mean the character played by Allison Janney on The West Wing, it’s Cregg.
I’m not a spring chicken, so I’ve had a few…
Helen Slater as Supergirl in '84.
Jennifer Connelly in Career Opportunities
Naomi Watts in King Kong
Penelope Ann Miller in Kindergarten Cop
Laura Dern in Teachers
Anne Archer in Patriot Games
Connie Nielsen in Soldier
Kate Beckinsale in Pearl Harbor
I know there’s more, but I can’t think of them at the moment.
Bridgette Wilson (-Sampras) in–gulp–“Billy Madison.”
Aside from a permanent crush on a certain blond elf, a part of my heart will always belong to Gordon Urquhart in Local Hero. I’d happily run off with him to run an inn on the Scottish coast any day, all he has to do is ask. Even 30 years later I still think Denis Lawson is a cutie-pie.
Amen. Funny, gorgeous, and funny.
Friend How can a movie about vampire strippers be the greatest movie of all time?
Me. How can a movie about vampire strippers NOT be the greatest movie of all time?
but Juliette Lewis is, at best, maybe kinda cute.
Shaun from Shaun of the Dead. He’s cowardly and lazy. But brave. And he loves his mum. We’d have a horrible adventure and then just sit on the couch.
If TV counts–Lennie Briscoe. Even The Fella loves watching L&O if it’s a Lennie ep.