Marilyn Monroe and Jessica Rabbit. Seriously.
Doctor Aki Ross (Final Fantasy) and Vera-Ellen (White Christmas).
Luke Cage (Marvel Comics) and the young Marlon Brando.
Since I put some thought into the question I thought it would be, Clive Owen and Goran Visnjic. 
She’ll never leave Fred, and we know it.
There’s a problem with psychotic?
Misako Kurata (from Kodomo no Omocha) and Ann Sheridan.
KP graduated from High School.
In that case, you have my blessing. And I’ll think no less of you for it.
Wonder Woman and Mother Theresa
Betty Rubble and Audrey Hepburn…
You need to seek therapy… quickly!
On second thought,
Irish McCalla and Cutey Honey.
We used to watch Sheena - Queen of the Jungle on the after school show on WKBW.